Kinetics of Ligand-Protein Dissociation from All-Atom Simulations: Are We There Yet?
来源期刊:BiochemistryDOI:10.1021/acs.biochem.8b00977
Biaryl-Forming Enzymes from Aspergilli Exhibit Substrate-Dependent Stereoselectivity.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00291
An Open-Source Plate Reader.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.8b00952
PIP2 Influences the Conformational Dynamics of Membrane bound KRAS4b.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00395
Taking toll on membranes: curious cases of bacterial β-barrel pore-forming toxins.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00783
Structural Basis for Rare Earth Element Recognition by Methylobacterium extorquens Lanmodulin.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.8b01019
Structure of a ferryl mimic in the archetypal iron(II)- and 2-(oxo)-glutarate-dependent dioxygenase, TauD.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00598
Eight-Letter DNA.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00274
A Disease-Causing Intronic Point Mutation C19G Alters Tau Exon 10 Splicing via RNA Secondary Structure Rearrangement.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00001
On Force and Form: Mechano-Biochemical Regulation of Extracellular Matrix.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00219
Nonphotosynthetic Biological CO2 Reduction.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.8b00937
A Lysine-Targeted Affinity Label for Serine-β-Lactamase Also Covalently Modifies New Delhi Metallo-β-lactamase-1 (NDM-1).
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00393
Human Indoleamine 2,3-Dioxygenase 1 Is an Efficient Mammalian Nitrite Reductase.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.8b01231
Bacterial Tetrabromopyrrole Debrominase Shares a Reductive Dehalogenation Strategy with Human Thyroid Deiodinase.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00318
Role of Gln114 in Spectral Tuning of a Long-Wavelength Sensitive Visual Pigment.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00340
Structural and Antiviral Studies of the Human Norovirus GII.4 Protease.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.8b01063
Insights into Thiotemplated Pyrrole Biosynthesis Gained from the Crystal Structure of Flavin-Dependent Oxidase in Complex with Carrier Protein.
来源期刊:BiochemistryDOI:10.2210/PDB6CY8/PDB
Detection of Incorporation of p-Coumaric Acid into Photoactive Yellow Protein Variants in Vivo.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00279
Identification of Filamin A Mechanobinding Partner I: Smoothelin Specifically Interacts with the Filamin A Mechanosensitive Domain 21.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00100
Incorporating 2-thiouracil into short dsRNA-binding PNAs for enhanced recognition of A-U pairs and for targeting a microRNA hairpin precursor.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00521
Crystal Structure and Substrate Specificity of the 8-oxo-dGTP Hydrolase NUDT1 from Arabidopsis thaliana.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.8b00950
3D protein structure determination using pseudocontact shifts of backbone amide protons generated by double-histidine Co2+-binding motifs at multiple sites.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00404
Multiplex Genome Engineering for Optimizing Bioproduction in Saccharomyces cerevisiae.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.8b01086
Restoration of miRNA-149 Expression by TmPyP4 Induced Unfolding of Quadruplex within Its Precursor.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.8b00880
Structural Evidence for Dimer-Interface-Driven Regulation of the Type II Cysteine Desulfurase, SufS.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.8b01122
Aerobic Enzymes and Their Radical SAM Enzyme Counterparts in Tetrapyrrole Pathways.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.8b00906
Structural Evidence for Dimer-Interface-Driven Regulation of the Type II Cysteine Desulfurase, SufS.
来源期刊:BiochemistryDOI:10.2210/PDB6MRH/PDB
Water networks and correlated motions in mutant IDH1 are critical for allosteric inhibitor binding and activity.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b01023
Glycosaminoglycans Induce Amyloid Self-Assembly of a Peptide Hormone by Concerted Secondary and Quaternary Conformational Transitions.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.8b01206
Munc13 Is a Molecular Target of Bryostatin 1.
来源期刊:BiochemistryDOI:10.1021/ACS.BIOCHEM.9B00427
Human Antibody Bispecifics through Phage Display Selection.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00037
A Fold-Independent Interface Residue Is Crucial for Complex Formation and Allosteric Signaling in Class I Glutamine Amidotransferases.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00286
Overexpression of Osmosensitive Ca2+-Permeable Channel TMEM63B Promotes Migration in HEK293T Cells.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00224
Structural and Functional Studies of the Membrane-Binding Domain of NADPH-Cytochrome P450 Oxidoreductase.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00130
Crossing the First Threshold: New Insights into the Influence of the Chemical Structure of Anionic Porphyrins on Plant Cell Wall Interactions and Photodynamic Cell Death Induction.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00107
New Insight Into the Mechanism of Anaerobic Heme Degradation.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00841
Calmodulin/Calcineurin Interaction Beyond the Calmodulin-binding Region Contributes to Calcineurin Activation.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00626
Combined Solution and Crystal Methods Reveal the Electrostatic Tethers That Provide a Flexible Platform for Replication Activities in the Bacteriophage T7 Replisome.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00525
Catalytic Cycle of Neisseria meningitidis CMP-Sialic Acid Synthetase Illustrated by High-Resolution Protein Crystallography.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00517
Synthesis and Target Identification of a Novel Electrophilic Warhead, 2-Chloromethylquinoline.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00359
Stiffness of cargo-motor linkage tunes Myosin VI motility and response to load.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00422
Structural and Functional Characterization of Sulfonium Carbon-Oxygen Hydrogen Bonding in the Deoxyamino Sugar Methyltransferase TylM1.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.8b01141
A Microfluidic-Based Microscopy Platform for Continuous Interrogation of Trypanosoma brucei during Environmental Perturbation.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.8b01269
TALEN-based chemically inducible, dimerization-dependent, sequence-specific nucleases.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00798
Structural Energy Landscapes and Plasticity of the Microstates of Apo E. coli cAMP Receptor Protein.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00895
Reversible membrane-tethering by ZipA determines FtsZ polymerization in two and three dimensions.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00378
Structural, Kinetic, and Mechanistic Analysis of an Asymmetric 4-Oxalocrotonate Tautomerase Trimer.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00303
Propagation of the Allosteric Signal in Phosphofructokinase from Bacillus stearothermophilus Examined by Methyl-TROSY NMR.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.9b00229
Synthetic Biology Approaches in Immunology.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.8b01081
Deciphering the Enzymatic Function of the Bovine Enteric Infection-Related Protein YfeJ from Salmonella enterica Serotype Typhimurium.
来源期刊:BiochemistryDOI:10.1021/acs.biochem.8b01283