Clinical Epigenetics

Hsa_circRNA_0054633 is highly expressed in gestational diabetes mellitus and closely related to glycosylation index

Gene domain-specific DNA methylation episignatures highlight distinct molecular entities of ADNP syndrome

Air pollution-induced placental alterations: an interplay of oxidative stress, epigenetics, and the aging phenotype?

Silencing or inhibition of H3K79 methyltransferase DOT1L induces cell cycle arrest by epigenetically modulating c-Myc expression in colorectal cancer

DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns

A genome-wide DNA methylation signature for SETD1B-related syndrome

The central nervous system tumor methylation classifier changes neuro-oncology practice for challenging brain tumor diagnoses and directly impacts patient care

Histone methyltransferases EHMT1 and EHMT2 (GLP/G9A) maintain PARP inhibitor resistance in high-grade serous ovarian carcinoma

Aberrantly hypermethylated tumor suppressor genes were identified in oral squamous cell carcinoma (OSCC)

Metabolic control of gene transcription in non-alcoholic fatty liver disease: the role of the epigenome

Methylation at cg05575921 of a smoking-related gene (AHRR) in non-smoking Taiwanese adults residing in areas with different PM2.5 concentrations

Oral vitamin C supplementation to patients with myeloid cancer on azacitidine treatment: Normalization of plasma vitamin C induces epigenetic changes

Genome-wide methylation profiling identified novel differentially hypermethylated biomarker MPPED2 in colorectal cancer

The E3 ubiquitin ligase RNF40 suppresses apoptosis in colorectal cancer cells

Increased methylation upstream of the MEG3 promotor is observed in acute myeloid leukemia patients with better overall survival

Prognostic implications and interaction of L1 methylation and p53 expression statuses in advanced gastric cancer

Cisplatin treatment of testicular cancer patients introduces long-term changes in the epigenome

Whole-genome DNA hyper-methylation in iPSC-derived dopaminergic neurons from Parkinson’s disease patients

Urinary DNA methylation biomarkers for prediction of prostate cancer upgrading and upstaging

Childhood traumatization is associated with differences in TRPA1 promoter methylation in female patients with multisomatoform disorder with pain as the leading bodily symptom

Epigenetic silencing of MEIS2 in prostate cancer recurrence

DNA methylation at an enhancer of the three prime repair exonuclease 2 gene (TREX2) is linked to gene expression and survival in laryngeal cancer

The phenotypic variations of multi-locus imprinting disturbances associated with maternal-effect variants of NLRP5 range from overt imprinting disorder to apparently healthy phenotype

Smoking-associated AHRR demethylation in cord blood DNA: impact of CD235a+ nucleated red blood cells

DNA methylation of individual repetitive elements in hepatitis C virus infection-induced hepatocellular carcinoma

Clustered protocadherins methylation alterations in cancer

Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis

DNA methylation profiling allows for characterization of atrial and ventricular cardiac tissues and hiPSC-CMs

Molecular and immune correlates of TIM-3 (HAVCR2) and galectin 9 (LGALS9) mRNA expression and DNA methylation in melanoma

Replicated methylation changes associated with eczema herpeticum and allergic response

RFX1 downregulation contributes to TLR4 overexpression in CD14+ monocytes via epigenetic mechanisms in coronary artery disease

Hyperglycemia affects global 5-methylcytosine and 5-hydroxymethylcytosine in blood genomic DNA through upregulation of SIRT6 and TETs

Loss of Msh2 and a single-radiation hit induce common, genome-wide, and persistent epigenetic changes in the intestine

Machine-learned analysis of global and glial/opioid intersection–related DNA methylation in patients with persistent pain after breast cancer surgery

Characterisation of DNA methylation changes in EBF3 and TBC1D16 associated with tumour progression and metastasis in multiple cancer types

SLCO4C1 promoter methylation is a potential biomarker for prognosis associated with biochemical recurrence-free survival after radical prostatectomy

Detecting multiple differentially methylated CpG sites and regions related to dimensional psychopathology in youths

ZBTB12 DNA methylation is associated with coagulation- and inflammation-related blood cell parameters: findings from the Moli-family cohort

Ovarian cancer detection by DNA methylation in cervical scrapings

Smoking index, lifestyle factors, and genomic instability assessed by single-cell gel electrophoresis: a cross-sectional study in subjects from Yucatan, Mexico

Random forest-based modelling to detect biomarkers for prostate cancer progression

Peripheral blood DNA methylation differences in twin pairs discordant for Alzheimer’s disease

Drug screening approach combines epigenetic sensitization with immunochemotherapy in cancer

Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma, or leukemia

Epigenetic age acceleration and metabolic syndrome in the coronary artery risk development in young adults study

Rheumatoid arthritis-relevant DNA methylation changes identified in ACPA-positive asymptomatic individuals using methylome capture sequencing

Correction to: DNA methylation signature is prognostic of choroid plexus tumor aggressiveness