PLoS Genetics

RPW8/HR repeats control NLR activation in Arabidopsis thaliana

RNase H1 directs origin-specific initiation of DNA replication in human mitochondria

Serotonin and neuropeptides are both released by the HSN command neuron to initiate Caenorhabditis elegans egg laying

Single-molecule dynamics and genome-wide transcriptomics reveal that NF-kB (p65)-DNA binding times can be decoupled from transcriptional activation

Ferritin heavy chain protects the developing wing from reactive oxygen species and ferroptosis

LINE-2 transposable elements are a source of functional human microRNAs and target sites

Native American admixture recapitulates population-specific migration and settlement of the continental United States

BZU2/ZmMUTE controls symmetrical division of guard mother cell and specifies neighbor cell fate in maize

The complex genetic architecture of shoot growth natural variation in Arabidopsis thaliana

Macrophages fine tune satellite cell fate in dystrophic skeletal muscle of mdx mice

Performing different kinds of physical exercise differentially attenuates the genetic effects on obesity measures: Evidence from 18,424 Taiwan Biobank participants

An ADAMTS3 missense variant is associated with Norwich Terrier upper airway syndrome

Meiotic gatekeeper STRA8 suppresses autophagy by repressing Nr1d1 expression during spermatogenesis in mice

Hormonal signaling cascades required for phototaxis switch in wandering Leptinotarsa decemlineata larvae

Intestinal NF-κB and STAT signalling is important for uptake and clearance in a Drosophila-Herpetomonas interaction model

Cyclophilin B control of lysine post-translational modifications of skin type I collagen

Role of α-Catenin and its mechanosensing properties in regulating Hippo/YAP-dependent tissue growth

Congenital lipodystrophy induces severe osteosclerosis

Quorum sensing and stress-activated MAPK signaling repress yeast to hypha transition in the fission yeast Schizosaccharomyces japonicus

LACK OF SYMBIONT ACCOMMODATION controls intracellular symbiont accommodation in root nodule and arbuscular mycorrhizal symbiosis in Lotus japonicus

miR-34 modulates wing polyphenism in planthopper

A secretion-enhancing cis regulatory targeting element (SECReTE) involved in mRNA localization and protein synthesis

A missense variant in FTCD is associated with arsenic metabolism and toxicity phenotypes in Bangladesh

The great hairball gambit

BCDIN3D regulates tRNAHis 3’ fragment processing

The PSMA8 subunit of the spermatoproteasome is essential for proper meiotic exit and mouse fertility

A functional regulatory variant of MYH3 influences muscle fiber-type composition and intramuscular fat content in pigs

The effects of manipulating levels of replication initiation factors on origin firing efficiency in yeast

Coacting enhancers can have complementary functions within gene regulatory networks and promote canalization

A small set of conserved genes, including sp5 and Hox, are activated by Wnt signaling in the posterior of planarians and acoels

NusG prevents transcriptional invasion of H-NS-silenced genes

Shuffling effector genes through mini-chromosomes

zfh2 controls progenitor cell activation and differentiation in the adult Drosophila intestinal absorptive lineage

The S phase checkpoint promotes the Smc5/6 complex dependent SUMOylation of Pol2, the catalytic subunit of DNA polymerase ε

HRPK-1, a conserved KH-domain protein, modulates microRNA activity during Caenorhabditis elegans development

Genetic screens reveal novel major and minor players in magnesium homeostasis of Staphylococcus aureus

Sumoylation of the DNA polymerase ε by the Smc5/6 complex contributes to DNA replication

Ataxin2 functions via CrebA to mediate Huntingtin toxicity in circadian clock neurons

Hypomorphic mutation of the mouse Huntington’s disease gene orthologue

Transcription-dependent spreading of the Dal80 yeast GATA factor across the body of highly expressed genes

Correction: Mutations in MITF and PAX3 Cause “Splashed White” and Other White Spotting Phenotypes in Horses

Correction: Loss of the Mia40a oxidoreductase leads to hepato-pancreatic insufficiency in zebrafish

Telomere-binding proteins Taz1 and Rap1 regulate DSB repair and suppress gross chromosomal rearrangements in fission yeast

Novel AU-rich proximal UTR sequences (APS) enhance CXCL8 synthesis upon the induction of rpS6 phosphorylation

Correction: Genetic variants in pachyonychia congenita-associated keratins increase susceptibility to tooth decay

The CspC pseudoprotease regulates germination of Clostridioides difficile spores in response to multiple environmental signals

Reshaping membranes to build mitochondrial DNA