MOLECULAR MEDICINE

CircRNA-9119 suppresses poly I:C induced inflammation in Leydig and Sertoli cells via TLR3 and RIG-I signal pathways

miR-122 promotes hepatic lipogenesis via inhibiting the LKB1/AMPK pathway by targeting Sirt1 in non-alcoholic fatty liver disease

Gut microbiota promote the inflammatory response in the pathogenesis of systemic lupus erythematosus

Tag-based next generation sequencing: a feasible and reliable assay for EGFR T790M mutation detection in circulating tumor DNA of non small cell lung cancer patients

YAP promotes the malignancy of endometrial cancer cells via regulation of IL-6 and IL-11

A rare functional variant of SHARPIN attenuates the inflammatory response and associates with increased risk of late-onset Alzheimer’s disease

Loss of intestinal sympathetic innervation elicits an innate immune driven colitis

Post-sepsis syndrome – an evolving entity that afflicts survivors of sepsis

The neuroprotective mechanisms of ginkgolides and bilobalide in cerebral ischemic injury: a literature review

PGK1 facilities cisplatin chemoresistance by triggering HSP90/ERK pathway mediated DNA repair and methylation in endometrial endometrioid adenocarcinoma

Increased proteinase 3 and neutrophil elastase plasma concentrations are associated with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes

Visualisation of HER2 homodimers in single cells from HER2 overexpressing primary formalin fixed paraffin embedded tumour tissue

Validation of impaired Transient Receptor Potential Melastatin 3 ion channel activity in natural killer cells from Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis patients

Integrated transcriptomic analysis reveals hub genes involved in diagnosis and prognosis of pancreatic cancer

Melatonin prevents bone destruction in mice with retinoic acid–induced osteoporosis

Astragalus polysaccharides suppresses high glucose-induced metabolic memory in retinal pigment epithelial cells through inhibiting mitochondrial dysfunction-induced apoptosis by regulating miR-195

Inhibition of microRNA-29a alleviates hyperoxia-induced bronchopulmonary dysplasia in neonatal mice via upregulation of GAB1

Role of 5-HT7 receptors in the immune system in health and disease

Curcumin induced oxidative stress attenuation by N-acetylcysteine co-treatment: a fibroblast and epithelial cell in-vitro study in idiopathic pulmonary fibrosis

Adverse transverse-tubule remodeling in a rat model of heart failure is attenuated with low-dose triiodothyronine treatment

Active repurposing of drug candidates for melanoma based on GWAS, PheWAS and a wide range of omics data

HDAC6 is associated with the formation of aortic dissection in human

IgG Galactosylation status combined with MYOM2-rs2294066 precisely predicts anti-TNF response in ankylosing spondylitis

aThe characteristics of glucose metabolism in the sulfonylurea receptor 1 knockout rat model

Angiopoietin 1 influences ischemic reperfusion renal injury via modulating endothelium survival and regeneration

Metabolomics analysis elucidates unique influences on purine / pyrimidine metabolism by xanthine oxidoreductase inhibitors in a rat model of renal ischemia-reperfusion injury

Tamoxifen and bone morphogenic protein-7 modulate fibrosis and inflammation in the peritoneal fibrosis model developed in uremic rats

Comparison of blood lipid profile/thyroid function markers between unipolar and bipolar depressed patients and in depressed patients with anhedonia or suicidal thoughts

FOXD1 mutations are related to repeated implantation failure, intra-uterine growth restriction and preeclampsia

The cholinergic anti-inflammatory pathway in resistant hypertension treated with renal denervation

Deficiency of sphingomyelin synthase 1 but not sphingomyelin synthase 2 reduces bone formation due to impaired osteoblast differentiation

Molecular expression, characterization and mechanism of ALAS2 gain-of-function mutants

PRSS1 mutation: a possible pathomechanism of pancreatic carcinogenesis and pancreatic cancer

CKD-602, a topoisomerase I inhibitor, induces apoptosis and cell-cycle arrest and inhibits invasion in cervical cancer

Retinal pigment epithelium degeneration caused by aggregation of PRPF31 and the role of HSP70 family of proteins

Disorders of FZ-CRD; insights towards FZ-CRD folding and therapeutic landscape

HMGB1 concentration measurements in trauma patients: assessment of pre-analytical conditions and sample material

Edaravone reduces oxidative stress and intestinal cell apoptosis after burn through up-regulating miR-320 expression

Differential network analysis and protein-protein interaction study reveals active protein modules in glucocorticoid resistance for infant acute lymphoblastic leukemia

Circulating tumor cells: a valuable marker of poor prognosis for advanced nasopharyngeal carcinoma

Club cell protein 16 in sera from trauma patients modulates neutrophil migration and functionality via CXCR1 and CXCR2

Fimasartan reduces neointimal formation and inflammation after carotid arterial injury in apolipoprotein E knockout mice

An immunoevasive strategy through clinically-relevant pan-cancer genomic and transcriptomic alterations of JAK-STAT signaling components

Mus musculus deficient for secretory antibodies show delayed growth with an altered urinary metabolome

Differentiation of adult human retinal pigment epithelial cells into dopaminergic-like cells in vitro and in the recipient monkey brain

Association between admission plasma 2-oxoglutarate levels and short-term outcomes in patients with acute heart failure: a prospective cohort study

Correction to: Plasma Fibrinogen Is a Natural Deterrent to Amyloid β-Induced Platelet Activation and Neuronal Toxicity