The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface.
来源期刊:Journal of Biological ChemistryDOI:10.2210/PDB6N3D/PDB
A conserved and buried edge-to-face aromatic interaction in small ubiquitin-like modifier (SUMO) has a role in SUMO stability and function.
来源期刊:Journal of Biological ChemistryDOI:10.2210/PDB6J4I/PDB
Two complementary alpha-fucosidases fromStreptococcus pneumoniaepromote complete degradation of host-derived carbohydrate antigens.
来源期刊:Journal of Biological ChemistryDOI:10.2210/pdb6orh/pdb
A ligand-induced structural change in fatty acid-binding protein 1 is associated with potentiation of peroxisome proliferator-activated receptor alpha agonists.
来源期刊:Journal of Biological ChemistryDOI:10.2210/PDB6DO7/PDB
Structural analysis of a vibrio phospholipase reveals an unusual Ser-His-chloride catalytic triad.
来源期刊:Journal of Biological ChemistryDOI:10.2210/PDB6JL0/PDB
Direct observation of intermediates in the SufS cysteine desulfurase reaction reveals functional roles of conserved active-site residues.
来源期刊:Journal of Biological ChemistryDOI:10.2210/PDB6O11/PDB
Identification of functionally important residues and structural features in a bacterial lignostilbene dioxygenase.
来源期刊:Journal of Biological ChemistryDOI:10.2210/PDB6OJT/PDB
Molecular and structural basis of nucleoside diphosphate kinase-mediated regulation of spore and sclerotia development in the fungusAspergillus flavus.
来源期刊:Journal of Biological ChemistryDOI:10.2210/PDB6K3H/PDB
Structural insight into metallocofactor maturation in carbon monoxide dehydrogenase.
来源期刊:Journal of Biological ChemistryDOI:10.2210/PDB6OND/PDB
Engineering nanomolar peptide ligands that differentially modulate EphA2 receptor signaling
来源期刊:Journal of Biological ChemistryDOI:10.2210/PDB6NKP/PDB
Productive reorientation of a bound oxime reactivator revealed in room-temperature X-ray structures of native and VX-inhibited human acetylcholinesterase.
来源期刊:Journal of Biological ChemistryDOI:10.2210/PDB6O66/PDB
X-ray crystallography-based structural elucidation of enzyme-bound intermediates along the 1‐deoxy‐d‐xylulose 5-phosphate synthase reaction coordinate.
来源期刊:Journal of Biological ChemistryDOI:10.2210/PDB6OUV/PDB
Evidence for distinct rate-limiting steps in the cleavage of alkenes by carotenoid cleavage dioxygenases.
来源期刊:Journal of Biological ChemistryDOI:10.2210/PDB6N20/PDB
Heat shock protein 104 (HSP104) chaperones soluble Tau via a mechanism distinct from its disaggregase activity.
来源期刊:Journal of Biological ChemistryDOI:10.2210/PDB6AHF/PDB
Structural insights into the catalytic mechanism of lovastatin hydrolase
来源期刊:Journal of Biological ChemistryDOI:10.2210/PDB6KJC/PDB
The steroid side-chain-cleaving aldolase Ltp2-ChsH2DUF35 is a thiolase superfamily member with a radically repurposed active site.
来源期刊:Journal of Biological ChemistryDOI:10.2210/PDB6OK1/PDB
Structural basis of the target-binding mode of the G protein-coupled receptor kinase-interacting protein in the regulation of focal adhesion dynamics.
来源期刊:Journal of Biological ChemistryDOI:10.2210/PDB6IUI/PDB