Transfer Learning with Deep Convolutional Neural Networks for Classifying Cellular Morphological Changes
来源期刊:Slas DiscoveryDOI:10.1177/2472555218818756
OCTN: A Small Transporter Subfamily with Great Relevance to Human Pathophysiology, Drug Discovery, and Diagnostics
来源期刊:SLAS DiscoveryDOI:10.1177/2472555218812821
Implementation of the NCI-60 Human Tumor Cell Line Panel to Screen 2260 Cancer Drug Combinations to Generate >3 Million Data Points Used to Populate a Large Matrix of Anti-Neoplastic Agent Combinations (ALMANAC) Database
来源期刊:SLAS DiscoveryDOI:10.1177/2472555218812429
NanoBiT Complementation to Monitor Agonist-Induced Adenosine A1 Receptor Internalization
来源期刊:Slas DiscoveryDOI:10.1177/2472555219880475
A Therapeutic Role for the F1FO-ATP Synthase
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219860448
Influence of Matrigel on Single- and Multiple-Spheroid Cultures in Breast Cancer Research
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219834698
Targeting RNA with Small Molecules: Identification of Selective, RNA-Binding Small Molecules Occupying Drug-Like Chemical Space
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219885373
Identification and Characterization of Inhibitors of a Neutral Amino Acid Transporter, SLC6A19, Using Two Functional Cell-Based Assays
来源期刊:SLAS DiscoveryDOI:10.1177/2472555218794627
Screening Approaches for Targeting Ribonucleoprotein Complexes: A New Dimension for Drug Discovery
来源期刊:SLAS DiscoveryDOI:10.1177/2472555218818065
Morphology-Based Analysis of Myoblasts for Prediction of Myotube Formation
来源期刊:SLAS DiscoveryDOI:10.1177/2472555218793374
Integrated Multiparametric High-Content Profiling of Endothelial Cells
来源期刊:Slas DiscoveryDOI:10.1177/2472555218820848
Identification of the Tetraspanin CD9 as an Interaction Partner of Organic Cation Transporters 1 and 2
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219859837
A Phenotypic Screening Assay Identifies Modulators of Diamond Blackfan Anemia
来源期刊:SLAS DiscoveryDOI:10.1177/2472555218823531
High-Content Imaging for Large-Scale Detection of Low-Affinity Extracellular Protein Interactions
来源期刊:Slas DiscoveryDOI:10.1177/2472555219879053
A Perspective on Extreme Open Science: Companies Sharing Compounds without Restriction
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219838210
Application of New Cellular and Microphysiological Systems to Drug Metabolism Optimization and Their Positioning Respective to In Silico Tools
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219831407
CRISPR: A Screener’s Guide
来源期刊:Slas DiscoveryDOI:10.1177/2472555219883621
Implementation of a High-Throughput Pilot Screen in Peptide Hydrogel-Based Three-Dimensional Cell Cultures
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219844570
Structures and Interactions of Transmembrane Targets in Native Nanodiscs
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219857691
EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology
来源期刊:Slas DiscoveryDOI:10.1177/2472555218816276
Evaluation of Machine Learning Classifiers to Predict Compound Mechanism of Action When Transferred across Distinct Cell Lines
来源期刊:Slas DiscoveryDOI:10.1177/2472555218820805
A High-Throughput BRET Cellular Target Engagement Assay Links Biochemical to Cellular Activity for Bruton’s Tyrosine Kinase
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219884881
Cellular Target Engagement Approaches to Monitor Epigenetic Reader Domain Interactions
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219896278
Drug Target Engagement Using Coupled Cellular Thermal Shift Assay—Acoustic Reverse-Phase Protein Array
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219897256
Image-Based Marker-Free Screening of GABAA Agonists, Antagonists, and Modulators
来源期刊:Slas DiscoveryDOI:10.1177/2472555219887142
Addition of Optimized Bovine Serum Albumin Level in a High-Throughput Caco-2 Assay Enabled Accurate Permeability Assessment for Lipophilic Compounds
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219848483
Development of a High-Throughput Cytometric Screen to Identify Anti-Wolbachia Compounds: The Power of Public–Private Partnership
来源期刊:Slas DiscoveryDOI:10.1177/2472555219838341
Medium-Throughput Detection of Hsp90/Cdc37 Protein–Protein Interaction Inhibitors Using a Split Renilla Luciferase-Based Assay
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219884033
Chemical Derivatization Enables MALDI-TOF-Based High-Throughput Screening for Microbial Trimethylamine (TMA)-Lyase Inhibitors
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219838216
Identification of Antimalarial Inhibitors Using Late-Stage Gametocytes in a Phenotypic Live/Dead Assay
来源期刊:SLAS DiscoveryDOI:10.1177/2472555218796410
xCELLanalyzer: A Framework for the Analysis of Cellular Impedance Measurements for Mode of Action Discovery
来源期刊:SLAS DiscoveryDOI:10.1177/2472555218819459
Current Progress on Equilibrative Nucleoside Transporter Function and Inhibitor Design
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219870123
Lysyl-tRNA Synthetase from Pseudomonas aeruginosa: Characterization and Identification of Inhibitory Compounds
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219873095
High-Throughput Implementation of the NanoBRET Target Engagement Intracellular Kinase Assay to Reveal Differential Compound Engagement by SIK2/3 Isoforms
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219893277
The Scripps Molecular Screening Center and Translational Research Institute
来源期刊:SLAS DiscoveryDOI:10.1177/2472555218820809
Novel Cell-Based Assay for Identification of LRRK2 Inhibitors Using Its Aberrant Regulation of a Pluripotency Gene
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219864086
A Sensitive and Selective Immunoassay for the Quantitation of Serum Latent Myostatin after In Vivo Administration of SRK-015, a Selective Inhibitor of Myostatin Activation
来源期刊:Slas DiscoveryDOI:10.1177/2472555219860779
High-Density Cell Arrays for Genome-Scale Phenotypic Screening
来源期刊:SLAS DiscoveryDOI:10.1177/2472555218818757
Development of a Bioluminescent High-Throughput Screening Assay for Nicotinamide Mononucleotide Adenylyltransferase (NMNAT)
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219879644
Live Cell Membranome cDNA Screen: A Novel Homogenous Live Cell Binding Assay to Study Membrane Protein-Ligand Interaction
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219873069
A Cell-Based Renilla Luminescence Reporter Plasmid Assay for High-Throughput Screening to Identify Novel FDA-Approved Drug Inhibitors of HPV-16 Infection
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219860771
Response to the Article “Enzyme–Inhibitor Interactions and a Simple, Rapid Method for Determining Inhibition Modality”
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219872211
Identification of Novel Compounds Enhancing SR-BI mRNA Stability through High-Throughput Screening
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219894543
Identification of Novel Mast Cell Activators Using Cell-Based High-Throughput Screening
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219834699
Rebuttal to Response to the Article “Enzyme–Inhibitor Interactions and a Simple, Rapid Method for Determining Inhibition Modality”
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219875106
Development of a Bacterial Macroarray for the Rapid Screening of Targeted Antibody-Secreted Hybridomas
来源期刊:SLAS DiscoveryDOI:10.1177/2472555218804990
DNA Switch: Toehold-Mediated DNA Isothermal Amplification for Dengue Serotyping
来源期刊:SLAS DiscoveryDOI:10.1177/2472555218791743
Generation of a Monoclonal Antibody against D-Dimer Using HTS-Based LiCA
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219878407
Reviewer List
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219831670
Novel 2-Benzoyl-6-(2,3-Dimethoxybenzylidene)-Cyclohexenol Confers Selectivity toward Human MLH1 Defective Cancer Cells through Synthetic Lethality
来源期刊:SLAS DiscoveryDOI:10.1177/2472555219831405