CELLULAR SIGNALLING

NanoBRET ligand binding at a GPCR under endogenous promotion facilitated by CRISPR/Cas9 genome editing.

Empagliflozin reduces high glucose-induced oxidative stress and miR-21-dependent TRAF3IP2 induction and RECK suppression, and inhibits human renal proximal tubular epithelial cell migration and epithelial-to-mesenchymal transition.

LncRNA NEAT1 promotes docetaxel resistance in prostate cancer by regulating ACSL4 via sponging miR-34a-5p and miR-204-5p.

Src family kinases, HCK and FGR, associate with local inflammation and tumour progression in colorectal cancer.

Lipoxin A4 restores oxidative stress-induced vascular endothelial cell injury and thrombosis-related factor expression by its receptor-mediated activation of Nrf2-HO-1 axis.

miR-382-5p modulates the ATRA-induced differentiation of acute promyelocytic leukemia by targeting tumor suppressor PTEN.

Heparan sulfate proteoglycan - A common receptor for diverse cytokines.

Interleukin-10 induces senescence of activated hepatic stellate cells via STAT3-p53 pathway to attenuate liver fibrosis.

A novel long non-coding RNA LINC00355 promotes proliferation of lung adenocarcinoma cells by down-regulating miR-195 and up-regulating the expression of CCNE1.

Altered recruitment of Lyn, Syk and ZAP-70 into lipid rafts of activated B cells in Systemic Lupus Erythematosus.

Photobiomodulation therapy decreases free fatty acid generation and release in adipocytes to ameliorate insulin resistance in type 2 diabetes.

TMEPAI/PMEPA1 inhibits Wnt signaling by regulating β-catenin stability and nuclear accumulation in triple negative breast cancer cells.

Fine particulate matter (PM2.5) enhances FcεRI-mediated signaling and mast cell function.

N4-acetylcytidine is required for sustained NLRP3 inflammasome activation via HMGB1 pathway in microglia.

Native and iron-saturated bovine lactoferrin differently hinder migration in a model of human glioblastoma by reverting epithelial-to-mesenchymal transition-like process and inhibiting interleukin-6/STAT3 axis.

β-Glucan from Saccharomyces cerevisiae induces SBD-1 production in ovine ruminal epithelial cells via the Dectin-1-Syk-NF-κB signaling pathway.

Butyrate mediated regulation of RNA binding proteins in the post-transcriptional regulation of inflammatory gene expression.

Jab1/Cops5 contributes to chemoresistance in breast cancer by regulating Rad51.

Up-regulation of long intergenic noncoding RNA 01296 in ovarian cancer impacts invasion, apoptosis and cell cycle distribution via regulating EMT.

Low expression of PDK1 inhibits renal cell carcinoma cell proliferation, migration, invasion and epithelial mesenchymal transition through inhibition of the PI3K-PDK1-Akt pathway.

Tumor-secreted GRP78 facilitates the migration of macrophages into tumors by promoting cytoskeleton remodeling.

Involvement of hyaluronan and CD44 in cancer and viral infections.

TRIM59 expression is regulated by Sp1 and Nrf1 in LPS-activated macrophages through JNK signaling pathway.

PDE10A mutations help to unwrap the neurobiology of hyperkinetic disorders.

TCF7L2 and EGR1 synergistic activation of transcription of LCN2 via an ERK1/2-dependent pathway in esophageal squamous cell carcinoma cells.

Role of the RNA-binding protein Bicaudal-C1 and interacting factors in cystic kidney diseases.

Phosphodiesterase 3B (PDE3B) antagonizes the anti-angiogenic actions of PKA in human and murine endothelial cells.

Role of calcium in adult onset polycystic kidney disease.

The effects of IFITM1 and IFITM3 gene deletion on IFNγ stimulated protein synthesis

Thiamethoxam inhibits blastocyst expansion and hatching via reactive-oxygen species-induced G2 checkpoint activation in pigs.

Osteogenic gene markers are epigenetically reprogrammed during contractile-to-calcifying vascular smooth muscle cell phenotype transition.

Increased LGALS3BP promotes proliferation and migration of oral squamous cell carcinoma via PI3K/AKT pathway.

Isomers of conjugated linoleic acid induce insulin resistance through a mechanism involving activation of protein kinase Cε in liver cells.

Epithelial cell plasticity defines heterogeneity in lung cancer.

Epigenetics and cell cycle regulation in cystogenesis.

Divergent effects of Wnt5b on IL-3- and GM-CSF-induced myeloid differentiation

Retinoic acid downregulates thiol antioxidant defences and homologous recombination while promotes A549 cells sensitization to cisplatin.

Divergent off-target effects of RSK N-terminal and C-terminal kinase inhibitors in cardiac myocytes.

A fission yeast platform for heterologous expression of mammalian adenylyl cyclases and high throughput screening.

Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA2 phosphorylation in experimental ischemic stroke.

Muscarinic receptor stimulation induces TASK1 channel endocytosis through a PKC-Pyk2-Src pathway in PC12 cells.

The interaction between PLEKHG2 and ABL1 suppresses cell growth via the NF-κB signaling pathway in HEK293 cells.

Identification of novel PCTAIRE-1/CDK16 substrates using a chemical genetic screen.

Bone morphogenetic protein 2 induces the activation of WNT/β-catenin signaling and human trophoblast invasion through up-regulating BAMBI.

Adrenoceptor α2A signalling countervails the taming effects of synchronous cyclic nucleotide-elevation on thrombin-induced human platelet activation and aggregation.

Corrigendum to ‘Inositol hexakisphosphate kinase 1 is a metabolic sensor in pancreatic β-cells’ [Cellular Signalling 46 (2018) 120–128]

Sustained GRK2-dependent CREB activation is essential for α2-adrenergic receptor-induced PC12 neuronal differentiation.