GENOMICS PROTEOMICS & BIOINFORMATICS

Progress and Challenges for Live-cell Imaging of Genomic Loci Using CRISPR-based Platforms

Single-cell Analysis of CAR-T Cell Activation Reveals A Mixed TH1/TH2 Response Independent of Differentiation

Whole Genome Analyses of Chinese Population and De Novo Assembly of A Northern Han Genome

Deciphering Brain Complexity Using Single-cell Sequencing

Proteomics Analysis of Lipid Droplets from the Oleaginous Alga Chromochloris zofingiensis Reveals Novel Proteins for Lipid Metabolism

Warburg Effects in Cancer and Normal Proliferating Cells: Two Tales of the Same Name

Stereotypes About Enterotype: the Old and New Ideas

GliomaDB: A Web Server for Integrating Glioma Omics Data and Interactive Analysis

Global Quantitative Mapping of Enhancers in Rice by STARR-seq

DeepCPI: A Deep Learning-based Framework for Large-scale in silico Drug Screening

SSCC: A Novel Computational Framework for Rapid and Accurate Clustering Large-scale Single Cell RNA-seq Data

CIRCexplorer3: A CLEAR Pipeline for Direct Comparison of Circular and Linear RNA Expression

Agricultural Risk Factors Influence Microbial Ecology in Honghu Lake

Machine Learning to Detect Alzheimer’s Disease from Circulating Non-coding RNAs

CircAST: Full-length Assembly and Quantification of Alternatively Spliced Isoforms in Circular RNAs

Transcriptome and Regulatory Network Analyses of CD19-CAR-T Immunotherapy for B-ALL

Novel Autoantibodies Related to Cell Death and DNA Repair Pathways in Systemic Lupus Erythematosus

Translational Informatics for Parkinson’s Disease: from Big Biomedical Data to Small Actionable Alterations

gFACs: Gene Filtering, Analysis, and Conversion to Unify Genome Annotations Across Alignment and Gene Prediction Frameworks

SPOT-Disorder2: Improved Protein Intrinsic Disorder Prediction by Ensembled Deep Learning

Challenges of Processing and Analyzing Big Data in Mesoscopic Whole-brain Imaging

Antibiotic Treatment Drives the Diversification of the Human Gut Resistome

The Fast Track for Microbiome Research

Identification of Cognitive Dysfunction in Patients with T2DM Using Whole Brain Functional Connectivity

Brain Banks Spur New Frontiers in Neuropsychiatric Research and Strategies for Analysis and Validation

How Microbes Shape Their Communities? A Microbial Community Model Based on Functional Genes

Functional Neuroimaging in the New Era of Big Data

SeqSQC: A Bioconductor Package for Evaluating the Sample Quality of Next-generation Sequencing Data

VPOT: A Customizable Variant Prioritization Ordering Tool for Annotated Variants

Big Data and the Brain: Peeking at the Future

Diversified Application of Barcoded PLATO (PLATO-BC) Platform for Identification of Protein Interactions

Meta-analysis Reveals Potential Influence of Oxidative Stress on the Airway Microbiomes of Cystic Fibrosis Patients

Chronic Food Antigen-specific IgG-mediated Hypersensitivity Reaction as A Risk Factor for Adolescent Depressive Disorder

PsyMuKB: An Integrative De Novo Variant Knowledge Base for Developmental Disorders

Application of Computational Biology to Decode Brain Transcriptomes

C3: Consensus Cancer Driver Gene Caller

Integrating Culture-based Antibiotic Resistance Profiles with Whole-genome Sequencing Data for 11,087 Clinical Isolates

Multi-omics Analysis of Primary Cell Culture Models Reveals Genetic and Epigenetic Basis of Intratumoral Phenotypic Diversity

Mapping Genome Variants Sheds Light on Genetic and Phenotypic Differentiation in Chinese

I3: A Self-organising Learning Workflow for Intuitive Integrative Interpretation of Complex Genetic Data

Gclust: A Parallel Clustering Tool for Microbial Genomic Data

In Memory of Vladimir B. Bajic (1952–2019)

A Computational Approach for Modeling the Allele Frequency Spectrum of Populations with Arbitrarily Varying Size

shinyChromosome: An R/Shiny Application for Interactive Creation of Non-circular Plots of Whole Genomes

Deep Learning Deepens the Analysis of Alternative Splicing

Deep Learning Deciphers Protein–RNA Interaction