Lysosomal dysfunction in proteinopathic neurodegenerative disorders: possible therapeutic roles of cAMP and zinc
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0439-2
Restoring Wnt/β-catenin signaling is a promising therapeutic strategy for Alzheimer’s disease
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0525-5
Modulation of mTOR and CREB pathways following mGluR5 blockade contribute to improved Huntington’s pathology in zQ175 mice
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0456-1
Predictable chronic mild stress promotes recovery from LPS-induced depression
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0463-2
Brain transcriptome analysis of a familial Alzheimer’s disease-like mutation in the zebrafish presenilin 1 gene implies effects on energy production
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0467-y
Roles for osteocalcin in brain signalling: implications in cognition- and motor-related disorders
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0444-5
Neuronal scaffolding protein spinophilin is integral for cocaine-induced behavioral sensitization and ERK1/2 activation
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0434-7
SGIP1α functions as a selective endocytic adaptor for the internalization of synaptotagmin 1 at synapses
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0464-1
The leukodystrophy mutation Polr3b R103H causes homozygote mouse embryonic lethality and impairs RNA polymerase III biogenesis
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0479-7
Anxiolytic effects of Formononetin in an inflammatory pain mouse model
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0453-4
Excitotoxic glutamate causes neuronal insulin resistance by inhibiting insulin receptor/Akt/mTOR pathway
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0533-5
Autism-like behaviors in male mice with a Pcdh19 deletion
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0519-3
The impact of RASopathy-associated mutations on CNS development in mice and humans
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0517-5
Baicalin regulates the dopamine system to control the core symptoms of ADHD
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0428-5
Motor skills mediated through cerebellothalamic tracts projecting to the central lateral nucleus
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0431-x
Regulation of global gene expression in brain by TMP21
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0460-5
Determination of circuit-specific morphological adaptations in ventral tegmental area dopamine neurons by chronic morphine
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0435-6
Expression of progenitor cell/immature neuron markers does not present definitive evidence for adult neurogenesis
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0522-8
Prenatal selective serotonin reuptake inhibitor (SSRI) exposure induces working memory and social recognition deficits by disrupting inhibitory synaptic networks in male mice
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0452-5
Differential regulation of Cav2.2 channel exon 37 variants by alternatively spliced μ-opioid receptors
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0524-6
MicroRNA profiling in adults with high-functioning autism spectrum disorder
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0508-6
TNF-α mediated upregulation of NaV1.7 currents in rat dorsal root ganglion neurons is independent of CRMP2 SUMOylation
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0538-0
Proteomic profiling of the neurons in mice with depressive-like behavior induced by corticosterone and the regulation of berberine: pivotal sites of oxidative phosphorylation
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0518-4
Plasma membrane localization of MLC1 regulates cellular morphology and motility
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0540-6
Conditioned stimulus presentations alter anxiety level in fear-conditioned mice
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0445-4
Identification of a molecular gating determinant within the carboxy terminal region of Cav3.3\u2009T-type channels
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0457-0
Voluntary wheel running promotes myelination in the motor cortex through Wnt signaling in mice
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0506-8
Cav3.2 calcium channel interactions with the epithelial sodium channel ENaC
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0433-8
Stimulation induces gradual increases in the thickness and curvature of postsynaptic density of hippocampal CA1 neurons in slice cultures
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0468-x
Circular RNA expression profile in the spinal cord of morphine tolerated rats and screen of putative key circRNAs
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0498-4
Ankyrin B and Ankyrin B variants differentially modulate intracellular and surface Cav2.1 levels
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0494-8
Transcriptional activation of USP16 gene expression by NFκB signaling
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0535-3
Novel nose poke-based temporal discrimination tasks with concurrent in vivo calcium imaging in freely moving mice
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0515-7
Inositol polyphosphate multikinase deficiency leads to aberrant induction of synaptotagmin-2 in the forebrain
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0480-1
Hyperpolarized [1-13C]lactate flux increased in the hippocampal region in diabetic mice
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0505-9
Analgesic effects of optogenetic inhibition of basolateral amygdala inputs into the prefrontal cortex in nerve injured female mice
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0529-1
RT2 PCR array screening reveals distinct perturbations in DNA damage response signaling in FUS-associated motor neuron disease
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0526-4
Systematic analysis of expression signatures of neuronal subpopulations in the VTA
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0530-8
Helix-A peptide prevents gp120-mediated neuronal loss
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0482-z
Peripheral blood metabolome predicts mood change-related activity in mouse model of bipolar disorder
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0527-3
Overexpression of activated CaMKII in the CA1 hippocampus impairs context discrimination, but not contextual conditioning
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0454-3
LAMP5 in presynaptic inhibitory terminals in the hindbrain and spinal cord: a role in startle response and auditory processing
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0437-4
The atypical cadherin flamingo determines the competence of neurons for activity-dependent fine-scale topography
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0531-7
Cortical ensemble activity discriminates auditory attentional states
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0502-z
Cell-specific expression of Epac2 in the subventricular and subgranular zones
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0537-1
Biological characteristics of transcription factor RelB in different immune cell types: implications for the treatment of multiple sclerosis
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0532-6
The high-affinity IgG receptor FcγRI modulates peripheral nerve injury-induced neuropathic pain in rats
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0499-3
The acute transcriptome response of the midbrain/diencephalon to injury in the adult mummichog (Fundulus heteroclitus)
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0542-4
Postsynaptic densities fragment into subcomplexes upon sonication
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0491-y
FGF receptors are required for proper axonal branch targeting in Drosophila
来源期刊:Molecular BrainDOI:10.1186/s13041-019-0503-y