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TOXICOLOGY MECHANISMS AND METHODS
ISSN：1537-6516

TOXICOLOGY MECHANISMS AND METHODS

TOXICOL MECH METHOD
学科领域：医学
是否预警：不在预警名单内
是否OA：否
录用周期：较慢,6-12周
新锐分区：医学4区
年发文量：88
影响因子：2.7
JCR分区：Q3

基本信息

毒理学机制和方法是一个同行评审的杂志，其目的是双重的。首先，该杂志包含了关于外来化学物质导致毒性组织损伤的机制的原创研究。感兴趣的化学物质包括工业化合物、环境污染物、危险废物、药物、杀虫剂和化学战剂。该杂志的范围从分子和细胞的作用机制到建立监管政策的机制证据的考虑。其次，该杂志涉及新的和现有的实验室方法、技术和设备的开发、验证和应用方面。讨论了各种研究方法，包括：标准和替代物种的体内研究体外研究和替代方法学分子、生化和细胞技术药代动力学和药效学数学建模和计算机程序法医学分析风险评估数据收集和分析。
1537-6516SCIE/Scopus收录
2.7
点击查看最新影响趋势>
2.9
新
2026年3月发布
点击查看历史分区趋势    >
大类学科小类学科Top期刊综述期刊
医学4区
TOXICOLOGY 毒理学
3区
否
N/A
新
WOS期刊SCI分区  2024-2025最新升级版
按JIF指标学科分区收集子录JIF分区JIF排名百分位
学科：TOXICOLOGY
SCIE
Q3
59/106
按JCR指标学科分区收集子录JCR分区JCR排名百分位
学科：TOXICOLOGY
SCIE
Q3
61/106
35
88
点击查看年发文量趋势图>
17%容易较慢,6-12周-TOXICOLOGY-
3.7%
点击查看自引率趋势图>
时间预警情况
2026年03月发布的新锐学术版不在预警名单中
2025年03月发布的2025版不在预警名单中
2024年02月发布的2024版不在预警名单中
2023年01月发布的2023版不在预警名单中
2021年12月发布的2021版不在预警名单中
2020年12月发布的2020版不在预警名单中
92.05%7.69%-
CiteScore：5.40
SJR：0.650
SNIP：0.747
学科类别分区排名百分位
大类：Environmental Science
小类：Health, Toxicology and Mutagenesis
Q2
64 / 148
大类：Environmental Science
小类：Toxicology
Q2
62 / 131

期刊高被引文献

Review of emerging concepts in nanotoxicology: opportunities and challenges for safer nanomaterial design
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1566425
In silico and in vivo analysis to identify the antidiabetic activity of beta sitosterol in adipose tissue of high fat diet and sucrose induced type-2 diabetic experimental rats
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2018.1545815
Quercetin protects cardiomyocytes against doxorubicin-induced toxicity by suppressing oxidative stress and improving mitochondrial function via 14-3-3γ
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2018.1564948
Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2018.1528650
Nephroprotective effect of cilostazol and verapamil against thioacetamide-induced toxicity in rats may involve Nrf2/HO-1/NQO-1 signaling pathway
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2018.1528648
Naringenin palliates cisplatin and doxorubicin gonadal toxicity in male rats
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2018.1512180
Mitochondria-dependent apoptosis in triptolide-induced hepatotoxicity is associated with the Drp1 activation
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1669247
Toxicity of ZnO nanoparticles (NPs) to THP-1 macrophages: interactions with saturated or unsaturated free fatty acids
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2018.1550130
Polychlorinated biphenyls promote cell survival through pyruvate kinase M2-dependent glycolysis in HeLa cells
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1584658
Allyl methyl sulfide, a garlic active component mitigates hyperglycemia by restoration of circulatory antioxidant status and attenuating glycoprotein components in streptozotocin-induced experimental rats
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2018.1534297
Vitamin E supplementation ameliorates the hepatotoxicity induced by Tramadol: toxicological, histological and immunohistochemical study
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1681043
Detection of opioids in umbilical cord lysates: an antibody-based rapid screening approach
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2018.1506850
High-fructose in drinking water initiates activation of inflammatory cytokines and testicular degeneration in rat
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2018.1543745
Excess iodine-induced lymphocytic impairment in adult rats
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2018.1528647
Toxic Effects of Chlorine Gas and Potential Treatments: A Literature Review.
来源期刊：Toxicology mechanisms and methodsDOI：10.1080/15376516.2019.1669244
Hepatoprotective effects of vitamin E against hexachlorobenzene-induced hepatotoxicity and oxidative stress in rats: histological, biochimical and antioxidant status changes
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2018.1506847
Genotoxicity evaluation of carbon monoxide and 1,3-butadiene using a new joint technology: the in vitro γH2AX HCS assay combined with air–liquid interface system
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2018.1477897
Neuromodulatory potential of phenylpropanoids; para-methoxycinnamic acid and ethyl-p-methoxycinnamate on aluminum-induced memory deficit in rats
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2018.1561779
In vitro mutagenicity and genotoxicity of raw and simulated leachates from plastic waste dumpsite
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1566426
Melatonin protects bone against cadmium-induced toxicity via activation of Wnt/β-catenin signaling pathway
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1701595
Acetamiprid, a neonicotinoid insecticide, induced cytotoxicity and genotoxicity in PC12 cells
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1624907
Toxicity of some broad-spectrum antibacterials in normal rat liver: the role of mitochondrial membrane permeability transition pore
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2018.1528651
Oxidative stress markers, trace elements, and endocrine disrupting chemicals in children with Hashimoto’s thyroiditis
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1646367
Hesperidin, a citrus flavonoid ameliorates hyperglycemia by regulating key enzymes of carbohydrate metabolism in streptozotocin-induced diabetic rats
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1646370
Effects of maternal exposure to BDE209 on neuronal development and transcription of iodothyronine deiodinase in offspring mice
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1624906
Triggering of apoptosis and cell cycle arrest by fennel and clove oils in Caco-2 cells: the role of combination
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1650149
Transient receptor potential ankyrin 1 (TRPA1)-mediated toxicity: friend or foe?
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1652872
Toxicity assessment of Lavandula officinalis extracts in Brine Shrimp (Artemia salina)
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1567892
Effects of timolol on Ca2+ handling and viability in human prostate cancer cells
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2018.1540024
IQOS – a heat-not-burn (HnB) tobacco product – chemical composition and possible impact on oxidative stress and inflammatory response. A systematic review
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1669245
Analysis of phthalate esters in two different baby care products available in United Arab Emirates
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2018.1512179
A multiparametric organ toxicity predictor for drug discovery
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1681044
Hep G2 cell culture confluence measurement in phase-contrast micrographs – a user-friendly, open-source software-based approach
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1695303
Preventive effects of nerve growth factor against colistin-induced autophagy and apoptosis in PC12 cells
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2018.1534298
Blocking of gastric acid induced histopathological alterations, enhancing of DNA content and proliferation of goblet cells in the acute lung injury mice models by nano-fenugreek oral administration
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1669249
Development of an acute, short-term exposure model for phosgene
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1636170
Effect of a beta-cypermethrin and emamectin benzoate pesticide mixture on reproductive toxicity in male mice in a greenhouse environment
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1669241
A novel evaluation method for determining drug-induced hepatotoxicity using 3D bio-printed human liver tissue
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1686795
Cadmium-calcium interference in the Rhinella arenarum oviduct
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1650147
The potential agents from food for preventing leukopenia induced by benzene: garlic preparations
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1650148
Crotonaldehyde-induced alterations in testicular enzyme function and hormone levels, and apoptosis in the testes of male Wistar rats are associated with oxidative damage
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1646369
An analytical strategy for the identification of carbamates, toxic alkaloids, phenobarbital and warfarin in stomach contents from suspected poisoned animals by thin-layer chromatography/ultraviolet detection
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1619213
Antidotal efficacies of the cyanide antidote candidate dimethyl trisulfide alone and in combination with cobinamide derivatives
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1585504
Syzygium Aromaticum Alleviates Cerium Chloride-Induced Neurotoxic Effect In The Adult Mice
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2018.1506849
p-Chloro-diphenyl diselenide attenuates plasma lipid profile changes and hepatotoxicity induced by nonionic surfactant tyloxapol in rats
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1669240
Comparative effects of scopolamine and phencynonate on organophosphorus nerve agent-induced seizure activity, neuropathology and lethality
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2018.1558322
Application of a DSS colitis model in toxicologically assessing norisoboldine
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1669242
Biochemical studies evaluating the chemopreventive potential of brucine in chemically induced mammary carcinogenesis of rats
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2018.1502387
Role of Smoking-Mediated molecular events in the genesis of oral cancers
来源期刊：Toxicology Mechanisms and MethodsDOI：10.1080/15376516.2019.1646372

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论文发表 2-4个月录用 7500+文章录用 不成功可退款
新
2026年3月发布（新锐分区）
大类学科小类学科Top期刊综述期刊
医学4区
TOXICOLOGY 毒理学
3区
否
N/A
2025年3月升级版
大类学科小类学科Top期刊综述期刊
医学4区
TOXICOLOGY 毒理学
3区
否
否
2023年12月旧的升级版
大类学科小类学科Top期刊综述期刊
医学4区
TOXICOLOGY 毒理学
4区
否
否