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XENOBIOTICA
ISSN：0049-8254

XENOBIOTICA

XENOBIOTICA
学科领域：医学
是否预警：不在预警名单内
是否OA：否
录用周期：约2.0个月
新锐分区：医学4区
年发文量：79
影响因子：1.2
JCR分区：Q4

基本信息

Xenobiotica涵盖七个主要领域，包括: 一般异种化学，包括与药物的代谢，处置和排泄有关的体外研究，以及其他异种生物，以及相关酶的结构，功能和调节临床药代动力学和代谢，涵盖了药代动力学和吸收，分布，动物药代动力学和代谢中药物和其他异种生物的代谢和排泄，涵盖了动物药代动力学，药物和其他异种生物的吸收，分布，代谢和排泄，定义为鉴定和功能表征编码异种生物代谢酶的多态性基因和可能导致酶改变的转运蛋白，对异种生物分子毒理学的细胞和临床反应，涉及毒性机制和分子水平异种生物转运蛋白的毒理学研究异种生物转运蛋白，涉及异种生物进入和离开细胞的载体蛋白的各个方面，以及它们对异种生物化学中动物和人体的药代动力学行为的影响，评论和评论的形式主要是对问题的批判性分析，其中作者就数据或特定实验方法或方法的相关性提供意见
0049-8254SCIE/Scopus收录
1.2
点击查看最新影响趋势>
1.5
新
2026年3月发布
点击查看历史分区趋势    >
大类学科小类学科Top期刊综述期刊
医学4区
PHARMACOLOGY & PHARMACY 药学
4区
TOXICOLOGY 毒理学
4区
否
N/A
新
WOS期刊SCI分区  2024-2025最新升级版
按JIF指标学科分区收集子录JIF分区JIF排名百分位
学科：PHARMACOLOGY & PHARMACY
SCIE
Q4
291/352
学科：TOXICOLOGY
SCIE
Q4
98/106
按JCR指标学科分区收集子录JCR分区JCR排名百分位
学科：PHARMACOLOGY & PHARMACY
SCIE
Q4
273/353
学科：TOXICOLOGY
SCIE
Q4
96/106
75
79
点击查看年发文量趋势图>
27%容易约2.0个月-医学-毒理学
8.3%
点击查看自引率趋势图>
时间预警情况
2026年03月发布的新锐学术版不在预警名单中
2025年03月发布的2025版不在预警名单中
2024年02月发布的2024版不在预警名单中
2023年01月发布的2023版不在预警名单中
2021年12月发布的2021版不在预警名单中
2020年12月发布的2020版不在预警名单中
79.75%9.56%1.71%
CiteScore：2.70
SJR：0.348
SNIP：0.408
学科类别分区排名百分位
大类：Pharmacology, Toxicology and Pharmaceutics
小类：Pharmacology
Q3
213 / 321
大类：Pharmacology, Toxicology and Pharmaceutics
小类：Health, Toxicology and Mutagenesis
Q3
108 / 148
大类：Pharmacology, Toxicology and Pharmaceutics
小类：Toxicology
Q3
96 / 131
大类：Pharmacology, Toxicology and Pharmaceutics
小类：Biochemistry
Q3
331 / 441

期刊高被引文献

Comprehensive preclinical pharmacokinetic evaluations of trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody-drug conjugate, in cynomolgus monkeys
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1531158
Pharmacokinetics and brain penetration study of chlorogenic acid in rats
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1445882
Interactions of organophosphorus pesticides with solute carrier (SLC) drug transporters
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1442030
Population pharmacokinetics and dosing regimen optimization of tacrolimus in Chinese pediatric hematopoietic stem cell transplantation patients
来源期刊：XenobioticaDOI：10.1080/00498254.2019.1601791
Metabolism of deltamethrin and cis- and trans-permethrin by rat and human liver microsomes, liver cytosol and plasma preparations
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1451011
Bisphenol S modulates concentrations of bisphenol A and oestradiol in female and male mice
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1480818
Metabolic profile elucidation of Zhi–Zi–Da–Huang decoction in rat intestinal bacteria using high-resolution mass spectrometry combined with multiple analytical perspectives
来源期刊：XenobioticaDOI：10.1080/00498254.2017.1414972
Absorption, distribution, metabolism and excretion of the P2Y12 receptor antagonist selatogrel after subcutaneous administration in healthy subjects
来源期刊：XenobioticaDOI：10.1080/00498254.2019.1646440
Absorption, distribution, metabolism, and excretion of radiolabeled naldemedine in healthy subjects
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1536815
Metabolic disposition of WTX101 (bis-choline tetrathiomolybdate) in a rat model of Wilson disease
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1443352
Effect of different doses of borneol on the pharmacokinetics of vinpocetine in rat plasma and brain after intraocular administration
来源期刊：XenobioticaDOI：10.1080/00498254.2019.1658139
Withanolide a penetrates brain via intra-nasal administration and exerts neuroprotection in cerebral ischemia reperfusion injury in mice
来源期刊：XenobioticaDOI：10.1080/00498254.2019.1709228
Metabolism and disposition of lesinurad, a uric acid reabsorption inhibitor, in humans
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1504257
Genetic polymorphisms of human hepatic OATPs: functional consequences and effect on drug pharmacokinetics
来源期刊：XenobioticaDOI：10.1080/00498254.2019.1629043
The current understanding of the interactions between nanoparticles and cytochrome P450 enzymes – a literature-based review
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1503360
Disposition and metabolism of [14C]lemborexant, a novel dual orexin receptor antagonist, in rats and monkeys
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1482509
Human urinary concentrations of monoisononyl phthalate estimated using physiologically based pharmacokinetic modeling and experimental pharmacokinetics in humanized-liver mice orally administered with diisononyl phthalate
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1471753
Twenty years of metabonomics: so what has metabonomics done for toxicology?
来源期刊：XenobioticaDOI：10.1080/00498254.2019.1697015
Minor contribution of CYP3A5 to the metabolism of hepatitis C protease inhibitor paritaprevir in vitro
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1524947
Effect Of epigallocatechin-3-gallate on the pharmacokinetics of amlodipine in rats
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1519732
Porcine interleukin-6 enhances the expression of CYP2C33 through a constitutive androstane receptor/retinoid X receptor-mediated pathway
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1438686
Uridine diphosphate glucuronosyltransferase 1A1
来源期刊：XenobioticaDOI：10.1080/00498254.2019.1617910
Absorption, disposition and metabolic pathway of amiselimod (MT-1303) in healthy volunteers in a mass balance study
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1525508
Lipidomics reveal aryl hydrocarbon receptor (Ahr)-regulated lipid metabolic pathway in alpha-naphthyl isothiocyanate (ANIT)-induced intrahepatic cholestasis
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1467065
Pharmacokinetics and lung distribution of macrolide antibiotics in sepsis model rats
来源期刊：XenobioticaDOI：10.1080/00498254.2019.1654633
Functional assessment of rat pulmonary flavin-containing monooxygenase activity
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1469804
19F-NMR-based determination of the absorption, metabolism and excretion of the oral phosphatidylinositol-3-kinase (PI3K) delta inhibitor leniolisib (CDZ173) in healthy volunteers
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1523488
Distribution and metabolism of 14C-sulfoquinovosylacylpropanediol (14C-SQAP) after a single intravenous administration in tumor-bearing mice
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1448949
The effect of elevated α1-acid glycoprotein on the pharmacokinetics of TAK-272 (SCO-272), an orally active renin inhibitor, in rats
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1480817
Dihydromyricetin affect the pharmacokinetics of triptolide in rats
来源期刊：XenobioticaDOI：10.1080/00498254.2019.1616851
Bergamottin can be used to assess CYP3A-mediated intestinal first-pass metabolism without affecting P-glycoprotein-mediated efflux in rats
来源期刊：XenobioticaDOI：10.1080/00498254.2019.1644389
The characteristics and mechanism of co-administration of lovastatin solid dispersion with kaempferol to increase oral bioavailability
来源期刊：XenobioticaDOI：10.1080/00498254.2019.1662136
Inhibitor selectivity of CNTs and ENTs
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1501832
Analysis of carboxylesterase 2 transcript variants in cynomolgus macaque liver
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1435927
Comparative study on the metabolism of the ergot alkaloids ergocristine, ergocryptine, ergotamine, and ergovaline in equine and human S9 fractions and equine liver preparations
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1542187
Mechanism-based pharmacokinetic–pharmacodynamic (PK–PD) modeling and simulation of oxaliplatin for hematological toxicity in rats
来源期刊：XenobioticaDOI：10.1080/00498254.2019.1601790
Computational and experimental studies on the interaction between butyrylcholinesterase and fluoxetine: implications in health and disease
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1506192
Food effect on meal administration time of pharmacokinetic profile of cilostazol, a BCS class II drug
来源期刊：XenobioticaDOI：10.1080/00498254.2019.1602746
Effects of sulfotanshinone sodium injection on the pharmacokinetics and pharmacodynamics of warfarin in rats in vivo
来源期刊：XenobioticaDOI：10.1080/00498254.2019.1681034
Comparison of pharmacokinetics of phytoecdysones and triterpenoid saponins of monomer, crude and processed Radix Achyranthis Bidentatae by UHPLC-MS/MS
来源期刊：XenobioticaDOI：10.1080/00498254.2019.1579946
Temsirolimus metabolic pathways revisited
来源期刊：XenobioticaDOI：10.1080/00498254.2019.1678793
Metabolomics reveals the effect of valproic acid on MCF-7 and MDA-MB-231 cells
来源期刊：XenobioticaDOI：10.1080/00498254.2019.1618510
Quantitative evaluation of hepatic and intestinal induction of CYP3A in clinical practice
来源期刊：XenobioticaDOI：10.1080/00498254.2019.1710620
The tissue distribution and excretion study of mosapride and its active des-p-fluorobenzyl and 4′-N-oxide metabolites in rats by ultra-high performance liquid chromatography-tandem mass spectrometry method
来源期刊：XenobioticaDOI：10.1080/00498254.2019.1588410
Effects of the ABCB1 and ABCG2 polymorphisms on the pharmacokinetics of afatinib in healthy Chinese volunteers
来源期刊：XenobioticaDOI：10.1080/00498254.2019.1610585
Rats and rabbits as pharmacokinetic screening tools for long acting intramuscular depots: case study with paliperidone palmitate suspension
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1464683
In vitro metabolism and in vivo pharmacokinetics of bentysrepinine (Y101), an investigational new drug for anti-HBV-infected hepatitis: focus on interspecies comparison
来源期刊：XenobioticaDOI：10.1080/00498254.2019.1646946
Pharmacogenetics and drug metabolism: historical perspective and appraisal
来源期刊：XenobioticaDOI：10.1080/00498254.2019.1668579
Disposition of [14C]LY2606368 following intravenous administration in patients with advanced and/or metastatic solid tumours
来源期刊：XenobioticaDOI：10.1080/00498254.2019.1702736
In vivo multiple metabolic pathways for a novel G protein-coupled receptor 119 agonist DS-8500a in rats: involvement of the 1,2,4-oxadiazole ring-opening reductive reaction in livers under anaerobic conditions
来源期刊：XenobioticaDOI：10.1080/00498254.2018.1514545

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论文发表 2-4个月录用 7500+文章录用 不成功可退款
新
2026年3月发布（新锐分区）
大类学科小类学科Top期刊综述期刊
医学4区
PHARMACOLOGY & PHARMACY 药学
4区
TOXICOLOGY 毒理学
4区
否
N/A
2025年3月升级版
大类学科小类学科Top期刊综述期刊
医学4区
PHARMACOLOGY & PHARMACY 药学
4区
TOXICOLOGY 毒理学
4区
否
否
2023年12月旧的升级版
大类学科小类学科Top期刊综述期刊
医学4区
PHARMACOLOGY & PHARMACY 药学
4区
TOXICOLOGY 毒理学
4区
否
否