PLOS MEDICINE

Discovery and validation of a prognostic proteomic signature for tuberculosis progression: A prospective cohort study

Risks of stillbirth and neonatal death with advancing gestation at term: A systematic review and meta-analysis of cohort studies of 15 million pregnancies

Clinical, microbiologic, and immunologic determinants of mortality in hospitalized patients with HIV-associated tuberculosis: A prospective cohort study

Redesigning care for older people to preserve physical and mental capacity: WHO guidelines on community-level interventions in integrated care

Progress in the HIV epidemic: Identifying goals and measuring success

Appraising the role of previously reported risk factors in epithelial ovarian cancer risk: A Mendelian randomization analysis

Integrating preexposure prophylaxis delivery in routine family planning clinics: A feasibility programmatic evaluation in Kenya

Long-term outcomes of an educational intervention to reduce antibiotic prescribing for childhood upper respiratory tract infections in rural China: Follow-up of a cluster-randomised controlled trial

Mediterranean-style diet in pregnant women with metabolic risk factors (ESTEEM): A pragmatic multicentre randomised trial

Independent and combined effects of improved water, sanitation, and hygiene (WASH) and improved complementary feeding on early neurodevelopment among children born to HIV-negative mothers in rural Zimbabwe: Substudy of a cluster-randomized trial

A simple real-time model for predicting acute kidney injury in hospitalized patients in the US: A descriptive modeling study

Lay health supporters aided by mobile text messaging to improve adherence, symptoms, and functioning among people with schizophrenia in a resource-poor community in rural China (LEAN): A randomized controlled trial

Impact of reduced dose of ready-to-use therapeutic foods in children with uncomplicated severe acute malnutrition: A randomised non-inferiority trial in Burkina Faso

The association between heatwaves and risk of hospitalization in Brazil: A nationwide time series study between 2000 and 2015

Frequency of cannabis and illicit opioid use among people who use drugs and report chronic pain: A longitudinal analysis

Rapid antiretroviral therapy initiation in low- and middle-income countries: A resource-based approach

Pharmacokinetics, optimal dosing, and safety of linezolid in children with multidrug-resistant tuberculosis: Combined data from two prospective observational studies

Cardiometabolic disease costs associated with suboptimal diet in the United States: A cost analysis based on a microsimulation model

Gender differences in grant and personnel award funding rates at the Canadian Institutes of Health Research based on research content area: A retrospective analysis

Estimating age-stratified influenza-associated invasive pneumococcal disease in England: A time-series model based on population surveillance data

Prediction of recurrent venous thrombosis in all patients with a first venous thrombotic event: The Leiden Thrombosis Recurrence Risk Prediction model (L-TRRiP)

Longitudinal engagement trajectories and risk of death among new ART starters in Zambia: A group-based multi-trajectory analysis

Social determinants of health in relation to firearm-related homicides in the United States: A nationwide multilevel cross-sectional study

Comparisons of exacerbations and mortality among regular inhaled therapies for patients with stable chronic obstructive pulmonary disease: Systematic review and Bayesian network meta-analysis

Contact tracing versus facility-based screening for active TB case finding in rural South Africa: A pragmatic cluster-randomized trial (Kharitode TB)

Operative versus non-operative treatment for 2-part proximal humerus fracture: A multicenter randomized controlled trial

Elective and nonelective cesarean section and obesity among young adult male offspring: A Swedish population–based cohort study

Antenatal magnesium sulphate and adverse neonatal outcomes: A systematic review and meta-analysis

Impact on child acute malnutrition of integrating a preventive nutrition package into facility-based screening for acute malnutrition during well-baby consultation: A cluster-randomized controlled trial in Burkina Faso

The gender-based violence and recovery centre at Coast Provincial General Hospital, Mombasa, Kenya: An integrated care model for survivors of sexual violence

Long-term mortality in mothers of infants with neonatal abstinence syndrome: A population-based parallel-cohort study in England and Ontario, Canada

Health checks and cardiovascular risk factor values over six years’ follow-up: Matched cohort study using electronic health records in England

Association of preterm birth with lipid disorders in early adulthood: A Swedish cohort study

Investigating causal pathways in severe falciparum malaria: A pooled retrospective analysis of clinical studies

Associations of fat mass and fat-free mass accretion in infancy with body composition and cardiometabolic risk markers at 5 years: The Ethiopian iABC birth cohort study

Research to improve differentiated HIV service delivery interventions: Learning to learn as we do

Validation of the prognostic value of NF-κB p65 in prostate cancer: A retrospective study using a large multi-institutional cohort of the Canadian Prostate Cancer Biomarker Network

Mortality and recovery following moderate and severe acute malnutrition in children aged 6–18 months in rural Jharkhand and Odisha, eastern India: A cohort study

Characterization of Parkinson’s disease using blood-based biomarkers: A multicohort proteomic analysis

Designing noninferiority tuberculosis treatment trials: Identifying practical advantages for drug regimens with acceptable effectiveness

Advances in clinical trial design for development of new TB treatments—Translating international tuberculosis treatment guidelines into national strategic plans: Experiences from Belarus, South Africa, and Vietnam

Impact of macronutrient supplements for children born preterm or small for gestational age on developmental and metabolic outcomes: A systematic review and meta-analysis

Addressing critical needs in the fight to end tuberculosis with innovative tools and strategies

Care practices and neonatal survival in 52 neonatal intensive care units in Telangana and Andhra Pradesh, India: A cross-sectional study

Correction: Socioeconomic position and use of healthcare in the last year of life: A systematic review and meta-analysis

Variation of all-cause and cause-specific mortality with body mass index in one million Swedish parent-son pairs: An instrumental variable analysis

Health and medical research for all: The challenge remains open