PHARMACOLOGICAL RESEARCH

The therapeutic role of long non‐coding RNAs in human diseases: A focus on the recent insights into autophagy

Hydrogen sulfide stabilizes atherosclerotic plaques in apolipoprotein E knockout mice.

The beneficial effects of N-acetyl cysteine (NAC) against obesity associated complications: A systematic review of pre-clinical studies.

Preclinical and clinical results regarding the effects of a plant-based antidiabetic formulation versus well established antidiabetic molecules.

Topoisomerase inhibitors: pharmacology and emerging nanoscale delivery systems.

Dysregulation of the Hippo pathway signaling in aging and cancer

β-blockers: their new life from hypertension to cancer and migraine.

Unveiling the guidance heterogeneity for genome-informed drug treatment interventions among regulatory bodies and research consortia.

Straight to the heart: Pleiotropic antiarrhythmic actions of oral anticoagulants.

Ginsenoside F1 promotes angiogenesis by activating the IGF-1/IGF1R pathway.

Saponins from Clematis mandshurica Rupr. regulates gut microbiota and its metabolites during alleviation of collagen-induced arthritis in rats.

Rev‐erb&agr; activation down‐regulates hepatic Pck1 enzyme to lower plasma glucose in mice

Functional daidzein enhances the anticancer effect of topotecan and reverses BCRP-mediated drug resistance in breast cancer.

Granulocyte death mediated by specific antibodies in intravenous immunoglobulin (IVIG).

Functional biological pacemaker generation by T‐Box18 protein expression via stem cell and viral delivery approaches in a murine model of complete heart block

Multi-dimensional Roles of Ketone Bodies in Cancer Biology: Opportunities for Cancer Therapy.

A novel class of cardioprotective small-molecule PTP inhibitors.

ER stress promotes antitumor effects in BRAFi/MEKi resistant human melanoma induced by natural compound 4‐nerolidylcathecol (4‐NC)

Inhibition of class I HDACs attenuates renal interstitial fibrosis in a murine model

Cognitive enhancers as a treatment for heroin relapse and addiction

Oleoylethanolamide inhibits glial activation via moudulating PPAR&agr; and promotes motor function recovery after brain ischemia

Autophagy inhibition plays a protective role against 3, 4‐methylenedioxymethamphetamine (MDMA)‐induced loss of serotonin transporters and depressive‐like behaviors in rats

Matrix metalloproteinase: An upcoming therapeutic approach for idiopathic pulmonary fibrosis.

Pharmacological preconditioning with the cellular stress inducer thapsigargin protects against experimental sepsis

Mahanine, A dietary phytochemical, represses mammary tumor burden in rat and inhibits subtype regardless breast cancer progression through suppressing self-renewal of breast cancer stem cells.

Role of transient receptor potential ankyrin 1 (TRPA1) on nociception caused by a murine model of breast carcinoma.

Mitochondrial carnitine palmitoyltransferase 2 is involved in Nε-(carboxymethyl)-lysine-mediated diabetic nephropathy.

Targeting STATs in neuroinflammation: The road less traveled!

Revisiting autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) mutations in the nicotinic acetylcholine receptor reveal an increase in efficacy regardless of stochiometry

Programming Changes in GLUT1 Mediated the Accumulation of AGEs and Matrix Degradation in the Articular Cartilage of Female Adult Rats after Prenatal Caffeine Exposure.

Use of oral contraceptives and risk of ulcerative colitis – A systematic review and meta‐analysis

Identification of an IKKβ inhibitor for inhibition of inflammation in vivo and in vitro.

Lead Bioactive Compounds of Aloe vera as Potential Anticancer Agent.

Megalin: A Bridge Connecting Kidney, the Renin-angiotensin System, and Atherosclerosis.

Destabilization of ROR1 enhances activity of ibrutinib against chronic lymphocytic leukemia in vivo.

Plumbagin inhibits cancer stem-like cells, angiogenesis and suppresses cell proliferation and invasion by targeting Wnt/β-catenin pathway in endocrine resistant breast cancer.

An oral 2-hydroxypropyl-β-cyclodextrin-loaded spirooxindole-pyrrolizidine derivative restores p53 activity via targeting MDM2 and JNK1/2 in hepatocellular carcinoma.

Growth hormone-releasing hormone (GHRH) deficiency promotes inflammation-associated carcinogenesis.

Striatal morphological and functional alterations induced by prenatal alcohol exposure

Sex-differences in factors and outcomes associated with adherence to statin therapy in primary care: need for customisation strategies.

N-octanoyl dopamine is superior to dopamine in protecting graft contractile function when administered to the heart transplant recipients from brain-dead donors.