PAIN

Migraine understood as a sensory threshold disease.

The role of Nav1.7 in human nociceptors: insights from human induced pluripotent stem cell–derived sensory neurons of erythromelalgia patients

Behavioural discrimination of noxious stimuli in infants is dependent on brain maturation

The prevalence and years lived with disability caused by low back pain in China, 1990 to 2016: findings from the global burden of disease study 2016

Investigating intraindividual pain variability: methods, applications, issues, and directions.

Cisplatin educates CD8+ T cells to prevent and resolve chemotherapy-induced peripheral neuropathy in mice.

Flunarizine as prophylaxis for episodic migraine: a systematic review with meta-analysis

Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury–associated peripheral sensory neuropathy via block of N- and T-type calcium channels

Kappa opioid signaling in the right central amygdala causes hind paw specific loss of diffuse noxious inhibitory controls in experimental neuropathic pain.

Dopamine receptor D2, but not D1, mediates descending dopaminergic pathway–produced analgesic effect in a trigeminal neuropathic pain mouse model

Targeting the CaVα-CaVβ interaction yields an antagonist of the N-type CaV2.2 channel with broad antinociceptive efficacy.

Long-term impact of adolescent chronic pain on young adult educational, vocational, and social outcomes.

The NLRP2 inflammasome in dorsal root ganglion as a novel molecular platform that produces inflammatory pain hypersensitivity.

Somatosensory profiles in acute herpes zoster and predictors of postherpetic neuralgia

The impact of anxiety on chronic musculoskeletal pain and the role of astrocyte activation

Meta-analysis of the psychometric properties of the Pain Catastrophizing Scale and associations with participant characteristics.

Positive allosteric modulators of nonbenzodiazepine &ggr;-aminobutyric acidA receptor subtypes for the treatment of chronic pain

CACNG2 polymorphisms associate with chronic pain after mastectomy

Distal infraorbital nerve injury: a model for persistent facial pain in mice.

Motor adaptation varies between individuals in the transition to sustained pain.

Prospective administration of anti–nerve growth factor treatment effectively suppresses functional connectivity alterations after cancer-induced bone pain in mice

The association between multiple sclerosis and pain medications

OPRM1 rs1799971, COMT rs4680, and FAAH rs324420 genes interact with placebo procedures to induce hypoalgesia.

Peripheral brain derived neurotrophic factor contributes to chronic osteoarthritis joint pain.

Neonatal vincristine administration modulates intrinsic neuronal excitability in the rat dorsal root ganglion and spinal dorsal horn during adolescence

A randomised, double blind, placebo-controlled crossover trial of the influence of the HCN channel blocker ivabradine in a healthy volunteer pain model: an enriched population trial.

Pain or nociception? Subjective experience mediates the effects of acute noxious heat on autonomic responses - corrected and republished.

Development and course of chronic widespread pain: The role of time and pain characteristics (the HUNT pain study).

Sex differences in the temporal development of pronociceptive immune responses in the tibia fracture mouse model.

Pain, opioid therapy, and survival: a needed discussion

Pain-related functional interference in patients with chronic neuropathic postsurgical pain: an analysis of registry data.

Nociceptin/orphanin FQ receptor modulates painful and fatigue symptoms in a mouse model of fibromyalgia.

Islet-cell autoantigen 69 mediates the antihyperalgesic effects of electroacupuncture on inflammatory pain by regulating spinal glutamate receptor subunit 2 phosphorylation through protein interacting with C-kinase 1 in mice

The rostromedial tegmental nucleus: a key modulator of pain and opioid analgesia.

Repressor element 1–silencing transcription factor drives the development of chronic pain states

Assessing pain in critically ill brain-injured patients: a psychometric comparison of three pain scales and videopupillometry.

Pain as a predictor of frailty over time among older Mexican Americans.

A randomized pilot study to investigate the effect of opioids on immunomarkers using gene expression profiling during surgery.

Temporal instability of salience network activity in migraine with aura.

Dynamic functional connectivity of migraine brain: a resting-state fMRI study.

Detangling red hair from pain: phenotype-specific contributions from different genetic variants in melanocortin-1 receptor.

High-threshold primary afferent supply of spinal lamina X neurons.

Recovery of physical activity after cesarean delivery and its relationship with pain.

Hedonic drinking engages a supraspinal inhibition of thermal nociception in adult rats

Rescue and concomitant analgesics in placebo-controlled trials of pharmacotherapy for neuropathic pain and low back pain.

Foot shock stress generates persistent widespread hypersensitivity and anhedonic behavior in an anxiety-prone strain of mice.

Pharmacological interventions for chronic pain in children: an overview of systematic reviews.