KIDNEY INTERNATIONAL

Arterial “inflammaging” drives vascular calcification in children on dialysis

Wnt/β-catenin links oxidative stress to podocyte injury and proteinuria.

Big science and big data in nephrology.

Multifactorial functions of the inflammasome component NLRP3 in pathogenesis of chronic kidney diseases.

Biological variation of measured and estimated glomerular filtration rate in patients with chronic kidney disease.

Chronic kidney disease and valvular heart disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

Safety and cardiovascular efficacy of spironolactone in dialysis-dependent ESRD (SPin-D): a randomized, placebo-controlled, multiple dosage trial.

Organelle crosstalk in the kidney.

Endothelin receptor-A mediates degradation of the glomerular endothelial surface layer via pathologic crosstalk between activated podocytes and glomerular endothelial cells.

Mononuclear phagocytes orchestrate prolyl hydroxylase inhibition-mediated renoprotection in chronic tubulointerstitial nephritis.

ATF6α downregulation of PPARα promotes lipotoxicity-induced tubulointerstitial fibrosis.

Aberrant DNA methylation of mTOR pathway genes promotes inflammatory activation of immune cells in diabetic kidney disease.

Prolyl hydroxylase inhibition protects the kidneys from ischemia via upregulation of glycogen storage.

CX3CL1-CX3CR1 interaction mediates macrophage-mesothelial cross talk and promotes peritoneal fibrosis.

Whole exome sequencing identified ATP6V1C2 as a novel candidate gene for recessive distal renal tubular acidosis.

Increased production and reduced urinary buffering of acid in uric acid stone formers is ameliorated by pioglitazone.

Mechanisms of GLP-1 receptor-independent renoprotective effects of the dipeptidyl peptidase type 4 inhibitor linagliptin in GLP-1 receptor knockout mice with 5/6 nephrectomy.

Detection and characterization of mosaicism in autosomal dominant polycystic kidney disease.

High-throughput sequencing contributes to the diagnosis of tubulopathies and familial hypercalcemia hypocalciuria in adults.

Activation of fibroblastic reticular cells in kidney lymph node during crescentic glomerulonephritis.

Dexmedetomidine reduces norepinephrine requirements and preserves renal oxygenation and function in ovine septic acute kidney injury.

Renal globotriaosylceramide facilitates tubular albumin absorption and its inhibition protects against acute kidney injury.

Tissue hypoxia, inflammation, and loss of glomerular filtration rate in human atherosclerotic renovascular disease.

Mutations in KIRREL1, a slit diaphragm component, cause steroid-resistant nephrotic syndrome.

The IgG-degrading enzyme of Streptococcus pyogenes causes rapid clearance of anti-glomerular basement membrane antibodies in patients with refractory anti-glomerular basement membrane disease.

DAMPening sterile inflammation of the kidney.

A propensity score matched analysis shows no adverse effect of early steroid withdrawal in non-diabetic kidney transplant recipients with and without glomerulonephritis.

Expanding opportunities and emerging challenges: broadening the scope of genetic testing in nephrology.

Apolipoprotein L1 (APOL1) risk variant toxicity depends on the haplotype background.

Transgenic zebrafish modeling low-molecular-weight proteinuria and lysosomal storage diseases.

Chronic kidney diseases in agricultural communities: report from a workshop.

Age-related changes in DNA methylation affect renal histology and post-transplant fibrosis.

Inhibition of the H3K4 methyltransferase MLL1/WDR5 complex attenuates renal senescence in ischemia reperfusion mice by reduction of p16INK4a.

Bioplasmonic paper-based assay for perilipin-2 non-invasively detects renal cancer.

Improving glomerular filtration rate estimation.

Genetic characterization of early renal changes in a novel mouse model of diabetic kidney disease.

The zinc fingers and homeoboxes 2 protein ZHX2 and its interacting proteins regulate upstream pathways in podocyte diseases.

Avian erythroblastosis virus E26 oncogene homolog-1 (ETS-1) plays a role in renal microvascular pathophysiology in the Dahl salt-sensitive rat.

How to sharpen a novel sword from AKI basic research.

Clinical features of genetically confirmed patients with primary hyperoxaluria identified by clinical indication versus familial screening.

Shiga toxin-producing Escherichia coli-associated hemolytic uremic syndrome in solid organ transplant recipients.

Noncanonical immunomodulatory activity of complement regulator C4BP(β-) limits the development of lupus nephritis.

Blood pressure modifies outcomes in patients with stage 3 to 5 chronic kidney disease.

Ferric citrate: cardio- and renoprotective in chronic kidney disease?

An unexpected role of steroid on podocytes: from zebrafish to human nephrotic syndrome?

The impact of epilepsy and its treatment in patients with end-stage renal disease.

ATHENA: wisdom and warfare in defining the role of de novo mTOR inhibition in kidney transplantation.