Targeting adenylate-forming enzymes with designed sulfonyladenosine inhibitors
来源期刊:The Journal of antibioticsDOI:10.1038/s41429-019-0171-2
Global Internet Data on the Interest in Antibiotics and Probiotics Generated by Google Trends
来源期刊:The Journal of AntibioticsDOI:10.3390/ANTIBIOTICS8030147
Synergistic combinations of anthelmintic salicylanilides oxyclozanide, rafoxanide, and closantel with colistin eradicates multidrug-resistant colistin-resistant Gram-negative bacilli
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0186-8
Novel 5-substituted derivatives of 2’-deoxy-6-azauridine with antibacterial activity
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0158-z
Diaporone A, a new antibacterial secondary metabolite from the plant endophytic fungus Diaporthe sp.
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0251-3
High-throughput identification of the sensitivities of an Escherichia coli ΔrecA mutant strain to various chemical compounds
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0160-5
Regioselective single pot C3-glycosylation of strophanthidol using methylboronic acid as a transient protecting group
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0172-1
Doxycycline inhibits pre-rRNA processing and mature rRNA formation in E. coli
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0149-0
Identification of novel in vitro antibacterial action of cloprostenol and evaluation of other non-antibiotics against multi-drug resistant A. baumannii
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0244-2
Aminomethyl spectinomycins: a novel antibacterial chemotype for biothreat pathogens
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0194-8
New semisynthetic teicoplanin derivatives have comparable in vitro activity to that of oritavancin against clinical isolates of VRE
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0164-1
Secondary metabolites produced by the citrus phytopathogen Phyllosticta citricarpa
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0154-3
Tunicamycin: chemical synthesis and biosynthesis
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0200-1
Antimicrobial anthraquinones from cultures of the ant pathogenic fungus Cordyceps morakotii BCC 56811
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-018-0135-y
Pro-caspase-3 protects cells from polymyxin B-induced cytotoxicity by preventing ROS accumulation
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0216-6
Rescrutiny of the sansanmycin biosynthetic gene cluster leads to the discovery of a novel sansanmycin analogue with more potency against Mycobacterium tuberculosis
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0210-z
Two new secondary metabolites from a mangrove-derived fungus Cladosporium sp. JS1-2
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0206-8
Liposidomycin, the first reported nucleoside antibiotic inhibitor of peptidoglycan biosynthesis translocase I: The discovery of liposidomycin and related compounds with a perspective on their application to new antibiotics
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0241-5
Synthesis and biological evaluation of (±)-hippolachnin and analogs
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0176-x
New azaphilones from Penicillium variabile, a fungal endophyte from roots of Aconitum vilmorinianum
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0250-4
Muraminomicins, new lipo-nucleoside antibiotics from Streptosporangium sp. SANK 60501-structure elucidations of muraminomicins and supply of the core component for derivatization
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0215-7
Coumamarin: a first coumarinyl calcium complex isolated from nature
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0207-7
Three new polyketides from a mangrove-derived fungus Colletotrichum gloeosporioides
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0178-8
Amycolatopsis alkalitolerans sp. nov., isolated from Gastrodia elata Blume
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0222-8
Fosfomycin and Staphylococcus aureus: transcriptomic approach to assess effect on biofilm, and fate of unattached cells
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0256-y
Structure and biological activity of Metarhizin C, a stereoisomer of BR-050 from Tolypocladium album RK17-F0007
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0229-1
Formal syntheses of (−)-isoretronecanol, (+)-laburnine, and a concise enantioselective synthesis of (+)-turneforcidine
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0169-9
De novo synthesis of novel bacterial monosaccharide fusaminic acid
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0170-3
Synthesis and biological activity of analogs of CPZEN-45, a novel antituberculosis drug
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0225-5
Antimicrobial Activity of Substituted Benzopentathiepin-6-amines
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0191-y
Cipralphelin, a new anti-oxidative N-cinnamoyl tripeptide produced by the deep sea-derived fungal strain Penicillium brevicompactum FKJ-0123
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0208-6
An inoculum-dependent culturing strategy (IDC) for the cultivation of environmental microbiomes and the isolation of novel endophytic Actinobacteria
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0226-4
Synergistic enhancement of beta-lactam antibiotics by modified tunicamycin analogs TunR1 and TunR2
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0220-x
Complete NMR assignment and absolute configuration of k4610422, a norditerpenoid inhibitor of testosterone-5α-reductase originally from Streptosporangium: rediscovery from a thermophilic Actinomadura
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0231-7
Isolation of depsipeptides and optimization for enhanced production of valinomycin from the North-Western Himalayan cold desert strain Streptomyces lavendulae
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0183-y
Chiral aminophosphines derived from hydroxyproline and their application in allene–imine [4\u2009+\u20092] annulation
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0181-0
Design, synthesis and antimicrobial studies of some polymyxin analogues
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0262-0
Design, synthesis, and antibacterial evaluation of novel derivatives of NPS-2143 for the treatment of methicillin-resistant S. aureus (MRSA) infection
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0177-9
Albicidin, a potent DNA gyrase inhibitor with clinical potential
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0228-2
A transannular approach toward lycopodine synthesis
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0155-2
Novel adenosine-derived inhibitors of Cryptosporidium parvum inosine 5′-monophosphate dehydrogenase
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0199-3
Construction of a 6/5/9-membered tricyclic structure of cladiellins via radical-polar crossover reaction
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0150-7
A letter from Professor Samuel J. Danishefsky
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0179-7
Professor Samuel J. Danishefsky, extraordinary synthetic chemist and great mentor
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0173-0
In honor of Professor Samuel J. Danishefsky
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0182-z
Sequential exo-mode oxacyclizations for the synthesis of the CD substructure of brevenal
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-018-0124-1
Rhizophins A and B, new sesquiterpenes from the culture broth of Coprinus rhizophorus
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0263-z
In vitro activity of eravacycline in combination with colistin against carbapenem-resistant A. baumannii isolates
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0188-6
Effect of C-2 substitution on the stability of non-traditional cephalosporins in mouse plasma
来源期刊:The Journal of antibioticsDOI:10.1038/s41429-019-0167-y
A new indole glycoside from Kitasatospora sp. MG372-hF19 carrying a 6-deoxy-α-l-talopyranose moiety
来源期刊:The Journal of AntibioticsDOI:10.1038/s41429-019-0258-9