Direct RNA nanopore sequencing of full-length coronavirus genomes provides novel insights into structural variants and enables modification analysis.
来源期刊:Genome researchDOI:10.1101/gr.247064.118
Structural variants in 3000 rice genomes.
来源期刊:Genome researchDOI:10.1101/gr.241240.118
Comprehensive, integrated, and phased whole-genome analysis of the primary ENCODE cell line K562.
来源期刊:Genome researchDOI:10.1101/gr.234948.118
A chromosome-scale assembly of the axolotl genome.
来源期刊:Genome researchDOI:10.1101/gr.241901.118
The origins and evolution of chromosomes, dosage compensation, and mechanisms underlying venom regulation in snakes.
来源期刊:Genome researchDOI:10.1101/gr.240952.118
A quantitative framework for characterizing the evolutionary history of mammalian gene expression.
来源期刊:Genome researchDOI:10.1101/gr.237636.118
Transcription factor activity and nucleosome organization in mitosis.
来源期刊:Genome researchDOI:10.1101/gr.243048.118
Decrypting noncoding RNA interactions, structures, and functional networks.
来源期刊:Genome researchDOI:10.1101/gr.247239.118
Anchor: trans-cell type prediction of transcription factor binding sites.
来源期刊:Genome researchDOI:10.1101/gr.237156.118
Ancient exapted transposable elements promote nuclear enrichment of human long noncoding RNAs.
来源期刊:Genome researchDOI:10.1101/gr.229922.117
Coexpression patterns define epigenetic regulators associated with neurological dysfunction.
来源期刊:Genome researchDOI:10.1101/gr.239442.118
Hormone-control regions mediate steroid receptor-dependent genome organization.
来源期刊:Genome researchDOI:10.1101/gr.243824.118
Experimental and pan-cancer genome analyses reveal widespread contribution of acrylamide exposure to carcinogenesis in humans.
来源期刊:Genome researchDOI:10.1101/gr.242453.118
TET2 binding to enhancers facilitates transcription factor recruitment in hematopoietic cells.
来源期刊:Genome researchDOI:10.1101/gr.239277.118
Defining TP53 pioneering capabilities with competitive nucleosome binding assays.
来源期刊:Genome researchDOI:10.1101/gr.234104.117
Whole-genome sequencing reveals high complexity of copy number variation at insecticide resistance loci in malaria mosquitoes.
来源期刊:Genome researchDOI:10.1101/gr.245795.118
Histone methyltransferase PRDM9 is not essential for meiosis in male mice.
来源期刊:Genome researchDOI:10.1101/gr.244426.118
SiCloneFit: Bayesian inference of population structure, genotype, and phylogeny of tumor clones from single-cell genome sequencing data
来源期刊:Genome ResearchDOI:10.1101/gr.243121.118
OMA standalone: orthology inference among public and custom genomes and transcriptomes.
来源期刊:Genome researchDOI:10.1101/gr.243212.118
Long-read single-molecule maps of the functional methylome.
来源期刊:Genome researchDOI:10.1101/gr.240739.118
Targeted delivery of CRISPR interference system against Fabp4 to white adipocytes ameliorates obesity, inflammation, hepatic steatosis, and insulin resistance.
来源期刊:Genome researchDOI:10.1101/gr.246900.118
Heterodimerization of TFAP2 pioneer factors drives epigenomic remodeling during neural crest specification.
来源期刊:Genome researchDOI:10.1101/gr.249680.119
Differences in firing efficiency, chromatin, and transcription underlie the developmental plasticity of the Arabidopsis DNA replication origins.
来源期刊:Genome researchDOI:10.1101/gr.240986.118
Contrasting roles of the RSC and ISW1/CHD1 chromatin remodelers in RNA polymerase II elongation and termination.
来源期刊:Genome researchDOI:10.1101/gr.242032.118
Early genome activation in Drosophila is extensive with an initial tendency for aborted transcripts and retained introns.
来源期刊:Genome researchDOI:10.1101/gr.242164.118
Mapping global and local coevolution across 600 species to identify novel homologous recombination repair genes.
来源期刊:Genome researchDOI:10.1101/gr.241414.118
4q-D4Z4 chromatin architecture regulates the transcription of muscle atrophic genes in facioscapulohumeral muscular dystrophy.
来源期刊:Genome researchDOI:10.1101/gr.233288.117
Brown rat demography reveals pre-commensal structure in eastern Asia before expansion into Southeast Asia.
来源期刊:Genome researchDOI:10.1101/gr.235754.118
Identifying loci under positive selection in complex population histories.
来源期刊:Genome researchDOI:10.1101/gr.246777.118
Cohesin occupancy and composition at enhancers and promoters are linked to DNA replication origin proximity in Drosophila.
来源期刊:Genome researchDOI:10.1101/gr.243832.118
Genome-wide analysis of polymerase III-transcribed Alu elements suggests cell-type-specific enhancer function.
来源期刊:Genome researchDOI:10.1101/gr.249789.119
A machine-learning approach for accurate detection of copy-number variants from exome sequencing.
来源期刊:Genome researchDOI:10.1101/gr.245928.118
High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma.
来源期刊:Genome researchDOI:10.1101/gr.246520.118
Dynamic reversal of random X-Chromosome inactivation during iPSC reprogramming.
来源期刊:Genome researchDOI:10.1101/gr.249706.119
A new approach for rare variation collapsing on functional protein domains implicates specific genic regions in ALS.
来源期刊:Genome researchDOI:10.1101/gr.243592.118
Identification of human silencers by correlating cross-tissue epigenetic profiles and gene expression.
来源期刊:Genome researchDOI:10.1101/gr.247007.118
Characterizing the nuclear and cytoplasmic transcriptomes in developing and mature human cortex uncovers new insight into psychiatric disease gene regulation.
来源期刊:Genome researchDOI:10.1101/gr.250217.119
MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network.
来源期刊:Genome researchDOI:10.1101/gr.238311.118
Convergent recombination cessation between mating-type genes and centromeres in selfing anther-smut fungi.
来源期刊:Genome researchDOI:10.1101/gr.242578.118
Kinetics of Xist-induced gene silencing can be predicted from combinations of epigenetic and genomic features.
来源期刊:Genome researchDOI:10.1101/gr.245027.118
Pediatric Cancer Variant Pathogenicity Information Exchange (PeCanPIE): a cloud-based platform for curating and classifying germline variants.
来源期刊:Genome researchDOI:10.1101/gr.250357.119
Transcriptional alterations in glioma result primarily from DNA methylation-independent mechanisms.
来源期刊:Genome researchDOI:10.1101/gr.249219.119
Circadian gene variants and the skeletal muscle circadian clock contribute to the evolutionary divergence in longevity across Drosophila populations.
来源期刊:Genome researchDOI:10.1101/gr.246884.118
Global analyses of the dynamics of mammalian microRNA metabolism
来源期刊:Genome ResearchDOI:10.1101/gr.251421.119
Environmentally induced plasticity of programmed DNA elimination boosts somatic variability in Paramecium tetraurelia.
来源期刊:Genome researchDOI:10.1101/gr.245332.118
A novel synthetic-genetic-array based yeast one-hybrid system for high discovery rate and short processing time.
来源期刊:Genome researchDOI:10.1101/gr.245951.118
Dynamics of microRNA expression during mouse prenatal development
来源期刊:Genome ResearchDOI:10.1101/gr.248997.119
Sequence determinants of polyadenylation-mediated regulation.
来源期刊:Genome researchDOI:10.1101/gr.247312.118
Genes essential for embryonic stem cells are associated with neurodevelopmental disorders
来源期刊:Genome ResearchDOI:10.1101/gr.250019.119
Fitness benefits of loss of heterozygosity in Saccharomyces hybrids.
来源期刊:Genome researchDOI:10.1101/gr.245605.118