Selonsertib (GS-4997), an ASK1 inhibitor, antagonizes multidrug resistance in ABCB1- and ABCG2-overexpressing cancer cells.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2018.10.007
A novel, liver-specific long noncoding RNA LINC01093 suppresses HCC progression by interaction with IGF2BP1 to facilitate decay of GLI1 mRNA.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.02.033
Treg-mediated acquired resistance to immune checkpoint inhibitors.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.05.003
tRNA-derived fragments and tRNA halves: The new players in cancers.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.03.012
CAR-NK for tumor immunotherapy: Clinical transformation and future prospects.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.11.033
Aptamer-functionalized liposomes for targeted cancer therapy.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.01.045
Long non-coding RNA HULC activates HBV by modulating HBx/STAT3/miR-539/APOBEC3B signaling in HBV-related hepatocellular carcinoma.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.04.008
New inhibitor of the TAp73 interaction with MDM2 and mutant p53 with promising antitumor activity against neuroblastoma.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.01.014
Glycochenodeoxycholate promotes hepatocellular carcinoma invasion and migration by AMPK/mTOR dependent autophagy activation.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.04.009
Towards the first targeted therapy for triple-negative breast cancer: Repositioning of clofazimine as a chemotherapy-compatible selective Wnt pathway inhibitor.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.02.018
Reversible regulation of SATB1 ubiquitination by USP47 and SMURF2 mediates colon cancer cell proliferation and tumor progression.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.01.039
Androgen deprivation-induced ZBTB46-PTGS1 signaling promotes neuroendocrine differentiation of prostate cancer.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2018.10.004
Single-cell transcriptome analysis reveals tumor immune microenvironment heterogenicity and granulocytes enrichment in colorectal cancer liver metastases.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.10.016
Emerging strategies in cancer therapy combining chemotherapy with immunotherapy.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.04.017
Regorafenib antagonizes BCRP-mediated multidrug resistance in colon cancer.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2018.10.032
Liquid biopsy in Ovarian cancer using Circulating Tumor DNA and Cells: Ready for Prime Time?
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.10.014
Human UTP14a promotes colorectal cancer progression by forming a positive regulation loop with c-Myc.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2018.10.010
Notch Signaling in Breast Cancer: From Pathway Analysis to Therapy.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.07.012
Inhibition of GSK-3β activity suppresses HCC malignant phenotype by inhibiting glycolysis via activating AMPK/mTOR signaling.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.08.003
Multiple myeloma cell-derived IL-32γ increases the immunosuppressive function of macrophages by promoting indoleamine 2,3-dioxygenase (IDO) expression.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.01.012
Preclinical comparison of regorafenib and sorafenib efficacy for hepatocellular carcinoma using multimodality molecular imaging.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.03.037
TRPM4 channel and cancer.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.04.012
Melatonin inhibits MLL-rearranged leukemia via RBFOX3/hTERT and NF-κB/COX-2 signaling pathways.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2018.11.037
miR-193a-3p inhibition of the Slug activator PAK4 suppresses non-small cell lung cancer aggressiveness via the p53/Slug/L1CAM pathway.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.01.027
Carbohydrate-based adjuvants activate tumor-specific Th1 and CD8+ T-cell responses and reduce the immunosuppressive activity of MDSCs.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2018.10.013
H22954, a novel long non-coding RNA down-regulated in AML, inhibits cancer growth in a BCL-2-dependent mechanism.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.03.055
Oncogene addiction as a foundation of targeted cancer therapy: The paradigm of the MET receptor tyrosine kinase.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2018.12.001
Sex Disparities in Cancer.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.08.017
Synergistic activity of BET inhibitor MK-8628 and PLK inhibitor Volasertib in preclinical models of medulloblastoma.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2018.12.012
Chromosome fragility in the buccal epithelium in patients with Fanconi anemia.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.12.008
Clinical Lipidomics In Understanding Of Lung Cancer: Opportunity And Challenge.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.08.014
Combined Bcl-2/Src inhibition synergize to deplete stem-like breast cancer cells.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.05.004
MicroRNA-182-5p regulates hedgehog signaling pathway and chemosensitivity of cisplatin-resistant lung adenocarcinoma cells via targeting GLI2.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.10.044
Anterior Gradient-2 monoclonal antibody inhibits lung cancer growth and metastasis by upregulating p53 pathway and without exerting any toxicological effects: A preclinical study.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.01.025
Tumor vasculature remodeling by radiation therapy increases doxorubicin distribution and efficacy.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.05.005
DMBX1 promotes tumor proliferation and regulates cell cycle progression via repressing OTX2-mediated transcription of p21 in lung adenocarcinoma cell.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.03.045
BIRC5 is a target for molecular imaging and detection of human pancreatic cancer.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.04.036
Vps4A mediates the localization and exosome release of β-catenin to inhibit epithelial-mesenchymal transition in hepatocellular carcinoma.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.04.035
Interference with the Bromodomain Epigenome Readers Drives p21 Expression and Tumor Senescence.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.06.019
Endothelin-converting enzyme-1 in cancer aggressiveness.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.03.033
NFX1-123 is highly expressed in cervical cancer and increases growth and telomerase activity in HPV 16E6 expressing cells.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.02.024
PI3Kα inhibitors sensitize esophageal squamous cell carcinoma to radiation by abrogating survival signals in tumor cells and tumor microenvironment.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.05.040
Mycoplasma infection promotes tumor progression via interaction of the mycoplasmal protein p37 and epithelial cell adhesion molecule in hepatocellular carcinoma.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.04.007
Nerve growth factor (NGF)-TrkA axis in head and neck squamous cell carcinoma triggers EMT and confers resistance to the EGFR inhibitor erlotinib.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.12.015
The covalent CDK7 inhibitor THZ1 enhances temsirolimus-induced cytotoxicity via autophagy suppression in human renal cell carcinoma.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.12.005
HS-173 as a novel inducer of RIP3-dependent necroptosis in lung cancer.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2018.12.006
Mutant p53R175H promotes cancer initiation in the pancreas by stabilizing HSP70.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.03.047
Technical differences between sequencing and microarray platforms impact transcriptomic subtyping of colorectal cancer.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.10.040
Aromatase-induced endogenous estrogen promotes tumour metastasis through estrogen receptor-α/matrix metalloproteinase 12 axis activation in castration-resistant prostate cancer.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.09.001
A pharmacogenomic analysis using L1000CDS2 identifies BX-795 as a potential anticancer drug for primary pancreatic ductal adenocarcinoma cells.
来源期刊:Cancer lettersDOI:10.1016/j.canlet.2019.08.002