Polychlorinated biphenyl exposures differentially regulate hepatic metabolism and pancreatic function: Implications for nonalcoholic steatohepatitis and diabetes
来源期刊：Toxicology and Applied PharmacologyDOI：10.1016/j.taap.2018.10.011
MitoQ ameliorates testis injury from oxidative attack by repairing mitochondria and promoting the Keap1‐Nrf2 pathway
来源期刊：Toxicology and Applied PharmacologyDOI：10.1016/j.taap.2019.03.001
Altered bile acid composition and disposition in a mouse model of non-alcoholic steatohepatitis.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.114664
Degradation of MCL-1 by bufalin reverses acquired resistance to osimertinib in EGFR-mutant lung cancer.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.114662
Prenatal and ancestral exposure to di(2-ethylhexyl) phthalate alters gene expression and DNA methylation in mouse ovaries.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.114629
Heme oxygenase-1 attenuates low-dose of deoxynivalenol-induced liver inflammation potentially associating with microbiota.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.04.020
Developmental exposure to perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) selectively decreases brain dopamine levels in northern leopard frogs.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.114623
Lung injury, oxidative stress and fibrosis in mice following exposure to nitrogen mustard.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.114798
Parental exposure to 2,2′,4,4′5 ‐ pentain polybrominated diphenyl ethers (BDE‐99) causes thyroid disruption and developmental toxicity in zebrafish
来源期刊：Toxicology and Applied PharmacologyDOI：10.1016/j.taap.2019.04.008
Kaempferol‐3‐O‐glucorhamnoside inhibits inflammatory responses via MAPK and NF‐&kgr;B pathways in vitro and in vivo
来源期刊：Toxicology and Applied PharmacologyDOI：10.1016/j.taap.2018.12.008
The interaction of zinc and the blood‐brain barrier under physiological and ischemic conditions
来源期刊：Toxicology and Applied PharmacologyDOI：10.1016/j.taap.2018.12.018
L‐Carnosine protects against Oxaliplatin‐induced peripheral neuropathy in colorectal cancer patients: A perspective on targeting Nrf‐2 and NF‐&kgr;B pathways
来源期刊：Toxicology and Applied PharmacologyDOI：10.1016/j.taap.2018.12.015
Clozapine‐induced reduction of l‐carnitine reabsorption via inhibition/down‐regulation of renal carnitine/organic cation transporter 2 contributes to liver lipid metabolic disorder in mice
来源期刊：Toxicology and Applied PharmacologyDOI：10.1016/j.taap.2018.11.007
Cordycepin sensitizes breast cancer cells toward irradiation through elevating ROS production involving Nrf2
来源期刊：Toxicology and Applied PharmacologyDOI：10.1016/j.taap.2018.12.006
Glucocorticoid programming mechanism for hypercholesterolemia in prenatal ethanol-exposed adult offspring rats.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.05.002
Multigenerational consequences of early‐life cannabinoid exposure in zebrafish
来源期刊：Toxicology and Applied PharmacologyDOI：10.1016/j.taap.2018.12.021
Counteracting tabun inhibition by reactivation by pyridinium aldoximes that interact with active center gorge mutants of acetylcholinesterase
来源期刊：Toxicology and Applied PharmacologyDOI：10.1016/j.taap.2019.04.007
Toxicokinetics and bioavailability of bisphenol AF following oral administration in rodents: A dose, species, and sex comparison
来源期刊：Toxicology and Applied PharmacologyDOI：10.1016/j.taap.2019.04.015
Progress in data interoperability to support computational toxicology and chemical safety evaluation.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.114707
The comparative effects of high dose atorvastatin and proprotein convertase subtilisin/kexin type 9 inhibitor on the mitochondria of oxidative muscle fibers in obese-insulin resistant female rats.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.114741
Low concentrations of perfluorooctane sulfonate repress osteogenic and enhance adipogenic differentiation of human mesenchymal stem cells
来源期刊：Toxicology and Applied PharmacologyDOI：10.1016/j.taap.2019.02.001
Polycyclic aromatic hydrocarbons exposure and hematotoxicity in occupational population: A two-year follow-up study.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.114622
Differential response to lead toxicity in rat primary microglia and astrocytes
来源期刊：Toxicology and Applied PharmacologyDOI：10.1016/j.taap.2018.11.010
Structure-activity study of acute neurobehavioral effects of cyclohexane, benzene, m-xylene, and toluene in rats.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.05.016
Modeling of antipsychotics-induced metabolic alterations in mice: An experimental approach precluding psychosis as a predisposing factor.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.114643
A multiplexed UPLC‐MS/MS assay for the simultaneous measurement of urinary safety biomarkers of drug‐induced kidney injury and phospholipidosis
来源期刊：Toxicology and Applied PharmacologyDOI：10.1016/j.taap.2019.01.012
Urban air pollution induces redox imbalance and epithelium hyperplasia in mice cornea.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.114770
Genotoxic and immunotoxic effects of the organophosphate metabolite diethyldithiophosphate (DEDTP) in Vivo
来源期刊：Toxicology and Applied PharmacologyDOI：10.1016/j.taap.2019.01.023
Early life inhalation exposure to mine tailings dust affects lung development
来源期刊：Toxicology and Applied PharmacologyDOI：10.1016/j.taap.2019.01.009
Gant61 ameliorates CCl4-induced liver fibrosis by inhibition of Hedgehog signaling activity.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.114853
Characterization of the modes of action and dose‐response relationship for thiocyanate on the thyroid hormone levels in rats using a computational approach
来源期刊：Toxicology and Applied PharmacologyDOI：10.1016/j.taap.2019.01.007
Acetyl‐macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti‐cancer effects with the Chk1/2 inhibitor AZD7762
来源期刊：Toxicology and Applied PharmacologyDOI：10.1016/j.taap.2019.01.005
Evidence that melatonin downregulates Nedd4-1 E3 ligase and its role in cellular survival.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.114686
Small molecule PIKfyve inhibitors as cancer therapeutics: Translational promises and limitations.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.114771
Cytotoxicity and oxidative stress induced by nickel and titanium ions from dental alloys on cells of gastrointestinal tract.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.114784
N-arylpiperazine-containing compound (C2): An enhancer of sunitinib in the treatment of pancreatic cancer, involving D1DR activation.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.114789
Cardiovascular variability and &bgr;‐ARs gene expression at two stages of doxorubicin – Induced cardiomyopathy
来源期刊：Toxicology and Applied PharmacologyDOI：10.1016/j.taap.2018.10.015
NF-κB-regulation of miR-155, via SOCS1/STAT3, is involved in the PM2.5-accelerated cell cycle and proliferation of human bronchial epithelial cells.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.114616
Evidence for the involvement of opioid and cannabinoid systems in the peripheral antinociception mediated by resveratrol
来源期刊：Toxicology and Applied PharmacologyDOI：10.1016/j.taap.2019.02.004
PFKFB3 promotes endotoxemia‐induced myocardial dysfunction through inflammatory signaling and apoptotic induction
来源期刊：Toxicology and Applied PharmacologyDOI：10.1016/j.taap.2019.02.007
Adoptive transfer of DMSO-induced regulatory T cells exhibits a similar preventive effect compared to an in vivo DMSO treatment for chemical-induced experimental encapsulating peritoneal sclerosis in mice.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.114641
The compartmentalised nature of the mechanisms governing superoxide formation and scavenging in cells exposed to arsenite.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.114766
Untargeted LC‐MS‐based metabonomics revealed that aristolochic acid I induces testicular toxicity by inhibiting amino acids metabolism, glucose metabolism, &bgr;‐oxidation of fatty acids and the TCA cycle in male mice
来源期刊：Toxicology and Applied PharmacologyDOI：10.1016/j.taap.2019.04.014
Dipeptidyl peptidase-4 inhibitor sitagliptin induces vasorelaxation via the activation of Kv channels and PKA.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.114799
Suppression of macrophages- Induced inflammation via targeting RAS and PAR-4 signaling in breast cancer cell lines.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.114773
The antineoplastic agent anacardic 6-pentadecyl salicylic acid produces immunomodulation in vivo via the activation of MAPKs.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.05.017
An increase in circulating B cells and B cell activation markers in peripheral blood is associated with cigarette smoking in a male cohort in Bangladesh.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.114783
Identification of differentially expressed genes and networks related to hepatic lipid dysfunction.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.114757
Coordinated cytochrome P450 expression in mouse liver and intestine under different dietary conditions during liver regeneration after partial hepatectomy
来源期刊：Toxicology and Applied PharmacologyDOI：10.1016/j.taap.2019.03.010
Structure-activity relationship study: Mechanism of cyto-genotoxicity of Nitropyrazole-derived high energy density materials family.
来源期刊：Toxicology and applied pharmacologyDOI：10.1016/j.taap.2019.114712
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