TOXICOLOGIC PATHOLOGY

Refinement, Reduction, and Replacement (3R) Strategies in Preclinical Testing of Medical Devices

Case Report: Canine Strain– and Study Condition–Dependent Formation of Renaut Bodies in Sciatic Nerves of Beagle Dogs

The Impact of Inhaled Ambient Ultrafine Particulate Matter on Developing Brain: Potential Importance of Elemental Contaminants

Sampling and Evaluating the Peripheral Nervous System

Toxicologic Pathology Forum*: Opinion on Integrating Innovative Digital Pathology Tools in the Regulatory Framework

Methods Optimization for Routine Sciatic Nerve Processing in General Toxicity Studies

International Regulatory Guiding Documents and Best Practice Recommendations on Peripheral Nervous System (PNS) Histopathologic Evaluation in Good Laboratory Practice (GLP)-Compliant Animal Toxicity Studies

Nerve Fiber Regeneration in Toxic Peripheral Neuropathy

Cardiopulmonary Health Effects of Airborne Particulate Matter: Correlating Animal Toxicology to Human Epidemiology

Normal Anatomy, Histology, and Spontaneous Pathology of the Kidney, and Selected Renal Biomarker Reference Ranges in the Cynomolgus Monkey

Proceedings of the 2019 National Toxicology Program Satellite Symposium

Endocrine Disruption and Reproductive Pathology

Peripheral Nerve Microscopic Changes Related to Study Procedures: Two Nonclinical Case Studies

Reevaluation of Hepatocellular Neoplasms in CD-1 Mice from a 2-year Oral Carcinogenicity Study with Permethrin

Spontaneous Cholangiofibrosis in a Wistar Rat

Toxicity and Safety Study of D-PLEX100 in a Sternal Surgical Defect in New Zealand White Rabbits

Intrarenal Renin–Angiotensin System Involvement in the Pathogenesis of Chronic Progressive Nephropathy—Bridging the Informational Gap Between Disciplines

Different Vascular Responses to a Bare Nitinol Stent in Porcine Femoral and Femoropopliteal Arteries

Long-Term Sequelae of Smoking and Cessation in Spontaneously Hypertensive Rats

Interstitial Adipocytes in the Beagle Dog and New Zealand White Rabbit Choroid Plexus

Safety Assessment of Food Additives: Case Example With Myrcene, a Synthetic Flavoring Agent

Previously Diagnosed Reticulum Cell Hyperplasia in Decalcified Rat Bone Marrow Stain Positive for Ionized Calcium Binding Adapter Molecule 1 (Iba1): A Monocytic/Macrophage Cell Marker

An IQ Consortium Perspective on The Scientific Committee on Health, Environmental and Emerging Risks Final Opinion on the Need for Nonhuman Primates in Biomedical Research, Production and Testing of Products and Devices (Update 2017)

Perspectives From the 12th Annual Minipig Research Forum: Early Inclusion of the Minipig in Safety Assessment Species Selection Should be the Standard Approach

Nonclinical Safety Assessment of a Long-Acting Recombinant PEGylated Factor Eight (BAY 94-9027) With a 60 kDa PEG

Evolving the Role of Discovery-focused Pathologists and Comparative Scientists in the Pharmaceutical Industry

Pathology in Ecological Research With Implications for One Health: Session Summary

Comparative Incidences and Biological Outcomes for Thymoma in Various Rat Strains in National Toxicology Program Studies

Development and Validation of an Image Analysis System for the Measurement of Cell Proliferation in Mammary Glands of Rats

Toxicologic Pathology Forum*: Opinion on Sexual Maturity and Fertility Assessment in Long-tailed Macaques (Macaca fascicularis) in Nonclinical Safety Studies

Pathological Features of Corneal Phospholipidosis in Juvenile White Rabbits Induced by Ocular Instillation of Chloroquine or Amiodarone

Histopathological Evaluation of Orthopedic Medical Devices: The State-of-the-art in Animal Models, Imaging, and Histomorphometry Techniques

What Is “Preclinical Device Pathology”: An Introduction of the Unfamiliar

Method for Combined Observation of Serial Sections of Stented Arteries Embedded in Resin by Light Microscopy and Transmission Electron Microscopy

Lipid Embolism in Obese Göttingen Minipigs

Scientific and Regulatory Policy Committee Points to Consider*: The Toxicologic Pathologist’s Role in the 3Rs

Pathology Approaches to Determine Safety and Efficacy of Cardiac Ablation Catheters

Biodegradability and Safety Study of LifeMesh™, a Novel Self-adhesive Mesh, in Sprague-Dawley Rats

Response to Letter to the Editor Regarding “Interstitial Adipocytes in the Beagle Dog and New Zealand White Rabbit Choroid Plexus”

Scientific and Regulatory Policy Committee Points to Consider*: Clinical and Anatomic Pathologists in Conduct of Vaccine Safety Studies.

Drug-induced Obstructive and Retrograde Nephropathy Associated with α2u-globulin in Male Rats

Medical Device Histology and Pathology: A Horse of a Different Color

Renal Papillary Rarefaction: An Artifact Mimicking Papillary Necrosis

Response to Letter to the Editor Regarding “Cholangiofibrosis and Related Cholangiocellular Neoplasms in Rodents”

Cytoplasmic Vacuolation and Tapetal Changes Induced by a Novel Analgesic Agent in Beagle Dogs

Pathological Safety Assessment in Preclinical Neurothrombectomy Studies

Comparison of the Class Effects of Antisense Oligonucleotides in CByB6F1-Tg(HRAS)2Jic and CD-1 Mice