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TOXICOLOGICAL SCIENCES
ISSN：1096-6080

TOXICOLOGICAL SCIENCES

TOXICOL SCI
学科领域：医学
是否预警：不在预警名单内
是否OA：否
录用周期：约2.0个月
新锐分区：医学3区
年发文量：149
影响因子：4.1
JCR分区：Q1

基本信息

《毒理学使命》是美国毒理学学会的官方期刊，其宗旨是发表毒理学领域的广泛而有影响力的研究。《毒理学科学》的主要重点是原创性研究文章。《毒理学科学》杂志还通过当代和系统综述、论坛文章和社论内容提供专家见解，讨论该领域的重要主题。《毒理学科学》的范围集中于广泛的影响毒理学研究，这些研究将推动毒理学多学科领域的发展，从基础研究到模型开发和应用，以及决策制定。提交材料将包括各种技术和方法，包括但不限于：生物信息学和计算生物学、生物化学、暴露科学、组织病理学、质谱分析、分子生物学、基于群体的科学、基于组织和细胞的系统以及全动物研究。鼓励采用综合方法，将现实的暴露情景与推动该领域向前发展的有影响力的分析相结合。
1096-6080SCIE/Scopus收录
4.1
点击查看最新影响趋势>
4.9
新
2026年3月发布
点击查看历史分区趋势    >
大类学科小类学科Top期刊综述期刊
医学3区
TOXICOLOGY 毒理学
2区
否
N/A
新
WOS期刊SCI分区  2024-2025最新升级版
按JIF指标学科分区收集子录JIF分区JIF排名百分位
学科：TOXICOLOGY
SCIE
Q1
23/106
按JCR指标学科分区收集子录JCR分区JCR排名百分位
学科：TOXICOLOGY
SCIE
Q1
22/106
164
149
点击查看年发文量趋势图>
10%0约2.0个月-医学-毒理学
4.9%
点击查看自引率趋势图>
时间预警情况
2026年03月发布的新锐学术版不在预警名单中
2025年03月发布的2025版不在预警名单中
2024年02月发布的2024版不在预警名单中
2023年01月发布的2023版不在预警名单中
2021年12月发布的2021版不在预警名单中
2020年12月发布的2020版不在预警名单中
88.59%21.55%4.17%
CiteScore：7.10
SJR：1.086
SNIP：0.952
学科类别分区排名百分位
大类：Pharmacology, Toxicology and Pharmaceutics
小类：Toxicology
Q1
31 / 131

期刊高被引文献

Role of Macrophages in Acute Lung Injury and Chronic Fibrosis Induced by Pulmonary Toxicants
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy309
Comparative Analysis of Zebrafish and Planarian Model Systems for Developmental Neurotoxicity Screens Using an 87-Compound Library
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy180
Automated Morphological Feature Assessment for Zebrafish Embryo Developmental Toxicity Screens
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy250
Multi-Behavioral Endpoint Testing of an 87-Chemical Compound Library in Freshwater Planarians
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy145
Identification of Modulators That Activate the Constitutive Androstane Receptor From the Tox21 10K Compound Library
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy242
Quantitative Systems Toxicology Analysis of In Vitro Mechanistic Assays Reveals Importance of Bile Acid Accumulation and Mitochondrial Dysfunction in TAK-875-Induced Liver Injury
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy253
Dichloroacetate Ameliorates Cardiac Dysfunction Caused by Ischemic Insults Through AMPK Signal Pathway—Not Only Shifts Metabolism
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy272
Chemical Activation of the Constitutive Androstane Receptor Leads to Activation of Oxidant-Induced Nrf2
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy231
Identifying Attributes That Influence In Vitro-to-In Vivo Concordance by Comparing In Vitro Tox21 Bioactivity Versus In Vivo DrugMatrix Transcriptomic Responses Across 130 Chemicals
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy220
Transient Receptor Potential Ion Channels Mediate Adherens Junctions Dysfunction in a Toluene Diisocyanate-Induced Murine Asthma Model
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy285
Regional Susceptibility to ER Stress and Protection by Salubrinal Following a Single Exposure to Deltamethrin
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy238
Prediction of Acute Oral Systemic Toxicity Using a Multifingerprint Similarity Approach
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy255
miR-149 Negative Regulation of mafA Is Involved in the Arsenite-Induced Dysfunction of Insulin Synthesis and Secretion in Pancreatic Beta Cells
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy150
Inhalation of ZnO Nanoparticles: Splice Junction Expression and Alternative Splicing in Mice
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy288
Repeatability and Reproducibility of the RTgill-W1 Cell Line Assay for Predicting Fish Acute Toxicity
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfz057
Resolving the Reversed Rate Effect of Calcium Channel Blockers on Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes and the Impact on In Vitro Cardiac Safety Evaluation
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy264
Targeting Smox Is Neuroprotective and Ameliorates Brain Inflammation in Cerebral Ischemia/Reperfusion Rats
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy300
Deciphering Adverse Outcome Pathway Network Linked to Bisphenol F Using Text Mining and Systems Toxicology Approaches
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfz214
Dose Effects of Ammonium Perfluorooctanoate on Lipoprotein Metabolism in APOE*3-Leiden.CETP Mice
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfz015
Employing Dietary Comparators to Perform Risk Assessments for Anti-Androgens Without Using Animal Data
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy245
Sex-Related Differences in Drug-Induced QT Prolongation and Torsades de Pointes: A New Model System with Human iPSC-CMs
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy239
A Performance Evaluation of Liver and Skeletal Muscle-Specific miRNAs in Rat Plasma to Detect Drug-Induced Injury
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy282
Quizalofop-p-Ethyl Induces Adipogenesis in 3T3-L1 Adipocytes
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfz097
Nicotine Promotes Human Papillomavirus (HPV)-Immortalized Cervical Epithelial Cells (H8) Proliferation by Activating RPS27a-Mdm2-P53 Pathway In Vitro
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy246
Association Between Meconium Acetaminophen and Childhood Neurocognitive Development in GESTE, a Canadian Cohort Study
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy222
Effects of Organophosphate Ester Flame Retardants on Endochondral Ossification in Ex Vivo Murine Limb Bud Cultures
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy301
Sex-Dependent Effects of 2,2′,3,5′,6-Pentachlorobiphenyl on Dendritic Arborization of Primary Mouse Neurons
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy277
A Novel Open Access Web Portal for Integrating Mechanistic and Toxicogenomic Study Results
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfz101
Associations Between Immune Phenotype and Inflammation in Murine Models of Irritant Contact Dermatitis
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy289
Bromate-induced Changes in p21 DNA Methylation and Histone Acetylation in Renal Cells
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfz016
Prenatal Exposure to Bisphenol A Analogues on Female Reproductive Functions in Mice
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfz014
Targeting Intracellular Calcium Stores Alleviates Neurological Morbidities in a DFP-Based Rat Model of Gulf War Illness
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfz070
Chimeric Mice With Humanized Livers Demonstrate Human-Specific Hepatotoxicity Caused by a Therapeutic Antibody Against TRAIL-Receptor 2/Death Receptor 5
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy228
Refining In Vitro Toxicity Models: Comparing Baseline Characteristics of Lung Cell Types
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfz001
Recovery From a Myocardial Infarction Is Impaired in Male C57bl/6\u2009N Mice Acutely Exposed to the Bisphenols and Phthalates That Escape From Medical Devices Used in Cardiac Surgery
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy276
Trovafloxacin-Induced Liver Injury: Lack in Regulation of Inflammation by Inhibition of Nucleotide Release and Neutrophil Movement
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy244
Effects of Acute Deltamethrin Exposure in Adult and Developing Sprague Dawley Rats on Acoustic Startle Response in Relation to Deltamethrin Brain and Plasma Concentrations
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy275
Physiologically Based Kinetic Modeling-Facilitated Reverse Dosimetry to Predict In Vivo Red Blood Cell Acetylcholinesterase Inhibition Following Exposure to Chlorpyrifos in the Caucasian and Chinese Population
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfz134
Arsenic May Act as a Pro-Metastatic Carcinogen Through Promoting Tumor Cell-Induced Platelet Aggregation
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy247
Nrf2 Activation Ameliorates Hepatotoxicity Induced by a Heme Synthesis Inhibitor
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy233
Allyl Sulfide Counteracts 1-Bromopropane-Induced Neurotoxicity by Inhibiting Neuroinflammation and Oxidative Stress
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy240
Sequence Variations in pxr (nr1i2) From Zebrafish (Danio rerio) Strains Affect Nuclear Receptor Function
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy269
Oxygen and Arsenite Synergize Phosphine Toxicity by Distinct Mechanisms
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy248
Exposure to 1,2-Dichloropropane Upregulates the Expression of Activation-Induced Cytidine Deaminase (AID) in Human Cholangiocytes Co-Cultured With Macrophages
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy280
The Critical Role of X Chromosome-Linked Inhibitor of Apoptosis (XIAP) in Differential Synergism Induced by Pentachlorophenol and Copper-1,10-Phenanthroline Complex in Normal and Cancer Liver Cells
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy307
A CRISPR/Cas9 Whole-Genome Screen Identifies Genes Required for Aryl Hydrocarbon Receptor-Dependent Induction of Functional CYP1A1
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfz111
All-trans Retinoic Acid Disrupts Development in Ex Vivo Cultured Fetal Rat Testes. II: Modulation of Mono-(2-ethylhexyl) Phthalate Toxicity
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfy283
Benzophenone-3 Passes Through the Blood-Brain Barrier, Increases the Level of Extracellular Glutamate, and Induces Apoptotic Processes in the Hippocampus and Frontal Cortex of Rats
来源期刊：Toxicological SciencesDOI：10.1093/TOXSCI/KFZ160
Characterization of Healthy Donor-Derived T-Cell Responses Specific to Telaprevir Diastereomers
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfz007
Corrigendum to “Dose-Related Severity Sequence, and Risk-Based Integration, of Chemically Induced Health Effects”
来源期刊：Toxicological SciencesDOI：10.1093/toxsci/kfz105

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学科领域：医学
影响因子：2
中科院分区： 3区
论文发表 2-4个月录用 7500+文章录用 不成功可退款
新
2026年3月发布
大类学科小类学科Top期刊综述期刊
医学3区
TOXICOLOGY 毒理学
2区
否
N/A
2025年3月升级版
大类学科小类学科Top期刊综述期刊
医学3区
TOXICOLOGY 毒理学
2区
否
否
2023年12月旧的升级版
大类学科小类学科Top期刊综述期刊
医学3区
TOXICOLOGY 毒理学
2区
否
否