Clinical-grade computational pathology using weakly supervised deep learning on whole slide images
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0508-1
Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers
来源期刊:Nature medicineDOI:10.1038/s41591-019-0367-9
Development of a gene-editing approach to restore vision loss in Leber congenital amaurosis type 10
来源期刊:Nature MedicineDOI:10.1038/s41591-018-0327-9
An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0422-6
Metagenomic and metabolomic analyses reveal distinct stage-specific phenotypes of the gut microbiota in colorectal cancer
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0458-7
Combined BRAF and MEK inhibition with PD-1 blockade immunotherapy in BRAF-mutant melanoma
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0476-5
Clinical lessons learned from the first leg of the CAR T cell journey
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0564-6
Atezolizumab plus cobimetinib and vemurafenib in BRAF-mutated melanoma patients
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0474-7
Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0400-z
Methionine is a metabolic dependency of tumor-initiating cells
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0423-5
A library of human gut bacterial isolates paired with longitudinal multiomics data enables mechanistic microbiome research
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0559-3
Small-molecule targeting of brachyury transcription factor addiction in chordoma
来源期刊:Nature medicineDOI:10.1038/s41591-018-0312-3
Distinct phenotype of CD4+ T cells driving celiac disease identified in multiple autoimmune conditions
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0403-9
Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis
来源期刊:Nature medicineDOI:10.1038/s41591-019-0393-7
Immune profiling of human tumors identifies CD73 as a combinatorial target in glioblastoma
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0694-x
Sensory feedback restoration in leg amputees improves walking speed, metabolic cost and phantom pain
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0567-3
Successful engraftment of gene-corrected hematopoietic stem cells in non-conditioned patients with Fanconi anemia
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0550-z
Developmental origins and emerging therapeutic opportunities for childhood cancer
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0383-9
Simultaneous detection of genotype and phenotype enables rapid and accurate antibiotic susceptibility determination
来源期刊:Nature medicineDOI:10.1038/s41591-019-0650-9
Genetic predisposition, modifiable risk factor profile and long-term dementia risk in the general population
来源期刊:Nature medicineDOI:10.1038/s41591-019-0547-7
Autism risk in offspring can be assessed through quantification of male sperm mosaicism
来源期刊:Nature medicineDOI:10.1038/s41591-019-0711-0
Glomerular filtration rate by differing measures, albuminuria and prediction of cardiovascular disease, mortality and end-stage kidney disease
来源期刊:Nature medicineDOI:10.1038/s41591-019-0627-8
Activating mutations in CSF-1R and additional receptor tyrosine kinases in histiocytic neoplasms
来源期刊:Nature medicineDOI:10.1038/s41591-019-0653-6
Generation of functional lungs via conditional blastocyst complementation using pluripotent stem cells
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0635-8
Benefit Corporation: a path to affordable gene therapies?
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0676-z
Time to revisit oligodendrocytes in multiple sclerosis
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0388-4
Publisher Correction: Non-invasive prenatal sequencing for multiple Mendelian monogenic disorders using circulating cell-free fetal DNA
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0391-9
Toward a broader response to cardiometabolic disease
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0642-9
Divergent effects of lipids on stroke
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0413-7
Antisense therapies pose a regulatory conundrum
来源期刊:Nature MedicineDOI:10.1038/D41591-019-00014-9
High-accuracy liquid biopsies
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0690-1
Reply to ‘Simpson’s paradox in proof-of-concept studies’
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0625-x
First CRISPR editing trial results assuage safety concerns.
来源期刊:Nature medicineDOI:10.1038/d41591-019-00019-4
Regulating microbiome manipulation
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0451-1
Unexpected clues emerge about why diets fail
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0632-y
Expanded non-invasive prenatal diagnostics
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0386-6
Author Correction: Microbiota therapy acts via a regulatory T cell MyD88/RORγt pathway to suppress food allergy
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0572-6
Author Correction: Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0698-6
Detecting opioid overdoses with smartphones
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0362-1
Author Correction: Reporting guidelines for clinical trials evaluating artificial intelligence interventions are needed
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0662-5
Finding diversity in the microbiome
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0494-3
Evidence mounts for a role for immune cells in the brain
来源期刊:Nature MedicineDOI:10.1038/D41591-019-00007-8
Prevention with a polypill
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0658-1
Gene editing fixes cystic fibrosis gene in mice before birth.
来源期刊:Nature medicineDOI:10.1038/D41591-019-00012-X
The processed food trap
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0489-0
Spreading the search
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0384-8
Nosocomial transmission of antibiotic resistance
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0589-x
Publisher Correction: Homeward bound
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0571-7
Turning up the heat on neglected diseases
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0514-3
Finding the edge of the seat
来源期刊:Nature MedicineDOI:10.1038/s41591-019-0557-5