Advances in Protein Chemistry and Structural Biology

Activating mutations of the gp130/JAK/STAT pathway in human diseases.

DNA repair by photolyases.

Dopamine signaling in the striatum.

When safeguarding goes wrong: Impact of oxidative stress on protein homeostasis in health and neurodegenerative disorders.

Controlling the balance between chromosome break repair pathways.

Intracellular protein complexes involved in synapse assembly in presynaptic neurons.

Protein stability and degradation in health and disease.

Functional and dysfunctional folding, association and aggregation of caseins.

Nucleobindins and encoded peptides: From cell signaling to physiology.

Intracellular signaling of the AMP-activated protein kinase.

Targeting DNA repair in precision medicine.

Replication stress: Driver and therapeutic target in genomically instable cancers.

Molecular signaling in bone cells: Regulation of cell differentiation and survival.

Cytotoxic species in amyloid-associated diseases: Oligomers or mature fibrils.

Structural and functional insights on the roles of molecular chaperones in the mistargeting and aggregation phenotypes associated with primary hyperoxaluria type I.

Aquaporin water channels: New perspectives on the potential role in inflammation.

Chaperones and retinal disorders.

Recent advances in computational studies of GPCR-G protein interactions.

The roles of cytosolic quality control proteins, SGTA and the BAG6 complex, in disease

Voices from the dead: The complex vocabulary and intricate grammar of dead cells.

A computational model to predict the structural and functional consequences of missense mutations in O6-methylguanine DNA methyltransferase.

The intrinsic and extrinsic factors that contribute to proteostasis decline and pathological protein misfolding.

Structure-function relationships in KDM7 histone demethylases.

Glutarate L-2-hydroxylase (CsiD/GlaH) is an archetype Fe(II)/2-oxoglutarate-dependent dioxygenase.

Claspin: From replication stress and DNA damage responses to cancer therapy.

LOXL1 folding in exfoliation glaucoma.

Influence of the reducing environment in the misfolding of wine proteins.

Relationship between mitofusin 2 and cancer.

Comparison of DNA and RNA substrate effects on TET2 structure.

Theoretical and computational advances in protein misfolding.

Non-heme iron enzyme-catalyzed complex transformations: Endoperoxidation, cyclopropanation, orthoester, oxidative C-C and C-S bond formation reactions in natural product biosynthesis.

Chromatin control in double strand break repair.

From traveler to homebody: Which signaling mechanisms sponge larvae use to become adult sponges?

Mass spectrometric approaches for profiling protein folding and stability.

Misfolding of vasopressin receptors: biased agonist pharmacochaperones as potential therapeutics.

Inflammatory response and its relation to sphingolipid metabolism proteins: Chaperones as potential indirect anti-inflammatory agents.