ACS Central Science

Dynamic and Cell-Infiltratable Hydrogels as Injectable Carrier of Therapeutic Cells and Drugs for Treating Challenging Bone Defects

A Laser Driven Flow Chemistry Platform for Scaling Photochemical Reactions with Visible Light

Reticular Chemistry in All Dimensions

Rapid Prediction of Electron–Ionization Mass Spectrometry Using Neural Networks

Promoting Angiogenesis in Oxidative Diabetic Wound Microenvironment Using a Nanozyme-Reinforced Self-Protecting Hydrogel

Quantum Chemistry on Quantum Computers: A Method for Preparation of Multiconfigurational Wave Functions on Quantum Computers without Performing Post-Hartree–Fock Calculations

Responsive Assembly of Silver Nanoclusters with a Biofilm Locally Amplified Bactericidal Effect to Enhance Treatments against Multi-Drug-Resistant Bacterial Infections

Targeted Protein Internalization and Degradation by ENDosome TArgeting Chimeras (ENDTACs)

Single Crystals of Electrically Conductive Two-Dimensional Metal–Organic Frameworks: Structural and Electrical Transport Properties

General Immobilization of Ultrafine Alloyed Nanoparticles within Metal–Organic Frameworks with High Loadings for Advanced Synergetic Catalysis

Brønsted Acid Scaling Relationships Enable Control Over Product Selectivity from O2 Reduction with a Mononuclear Cobalt Porphyrin Catalyst

Carbons with Regular Pore Geometry Yield Fundamental Insights into Supercapacitor Charge Storage

Thermodynamic Considerations for Optimizing Selective CO2 Reduction by Molecular Catalysts

Synthetic, Zwitterionic Sp1 Oligosaccharides Adopt a Helical Structure Crucial for Antibody Interaction

Principles of Inter-Amino-Acid Recognition Revealed by Binding Energies between Homogeneous Oligopeptides

Polariton Chemistry: Action in the Dark

Mapping the Azolog Space Enables the Optical Control of New Biological Targets

A Telescoping View of Solute Architectures in a Complex Fluid System

Effective Distance for DNA-Mediated Charge Transport between Repair Proteins

Stretchable and Fully Degradable Semiconductors for Transient Electronics

Hybrid Anatase/Rutile Nanodots-Embedded Covalent Organic Frameworks with Complementary Polysulfide Adsorption for High-Performance Lithium–Sulfur Batteries

A Novel (1,4)-β-Linked Glucoxylan Is Synthesized by Members of the Cellulose Synthase-Like F Gene Family in Land Plants

Linked Toll-Like Receptor Triagonists Stimulate Distinct, Combination-Dependent Innate Immune Responses

The Importance of Salt-Enhanced Electrostatic Repulsion in Colloidal Crystal Engineering with DNA

Trapping and Electron Paramagnetic Resonance Characterization of the 5′dAdo• Radical in a Radical S-Adenosyl Methionine Enzyme Reaction with a Non-Native Substrate

Characterization of Reactive Organometallic Species via MicroED

In Vivo Multicolor Imaging with Fluorescent Probes Revealed the Dynamics and Function of Osteoclast Proton Pumps

Single-Molecule Mechanistic Study of Enzyme Hysteresis

Spontaneous Isomerization of Long-Lived Proteins Provides a Molecular Mechanism for the Lysosomal Failure Observed in Alzheimer’s Disease

Mechanistic Basis for Ribosomal Peptide Backbone Modifications

Discovery of Volatile Biomarkers of Parkinson’s Disease from Sebum

An Asymmetric Electrochemical System with Complementary Tunability in Hydrophobicity for Selective Separations of Organics

Two Tryptophans Are Better Than One in Accelerating Electron Flow through a Protein

Amphiphile-Based Complex Fluids: The Self-Assembly Ensemble as Protagonist

Molecular Basis of Broad Spectrum N-Glycan Specificity and Processing of Therapeutic IgG Monoclonal Antibodies by Endoglycosidase S2

Exploring the Free Energy Landscape To Predict the Surfactant Adsorption Isotherm at the Nanoparticle–Water Interface

Utilizing Chemical Intuition in the Search for New Quantum Materials

A Chemical Genetic Method for Monitoring Genome-Wide Dynamics of O-GlcNAc Turnover on Chromatin-Associated Proteins

Building Scaffolds To Rebuild Kidneys

The Shifting Picture of Rewritable Paper

A Conversation with Kenichiro Itami

Charge Transport Communication through DNA by Protein Fe–S Clusters: How Far Is Not Too Far?

A Conversation with Melissa Denecke

The Key Intermediate in Radical S-Adenosyl-methionine Catalysis: Caught in the Act

Chronoprints: Identifying Samples by Visualizing How They Change over Space and Time

A Conversation with Jackie Ying

A Novel Split Reporter Uncages New Possibilities