EXPERIMENTAL ANIMALS

Bone microstructure and metabolism changes under the combined intervention of ketogenic diet with intermittent fasting: an in vivo study of rats

Osthole improves therapy for osteoporosis through increasing autophagy of mesenchymal stem cells

Astragaloside IV reduces cardiomyocyte apoptosis in a murine model of coxsackievirus B3-induced viral myocarditis

Continuous measurement of locomotor activity during convalescence and acclimation in group-housed rats

Pathological characteristics of Ccdc85c knockout rats: a rat model of genetic hydrocephalus

The acute pulmonary toxicity in mice induced by Staphylococcus aureus, particulate matter, and their combination

Inhibition of long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 attenuates high glucose-induced cardiomyocyte apoptosis via regulation of miR-181a-5p

Minimum environmental enrichment is effective in activating antitumor immunity to transplanted tumor cells in mice

Analysis of amino acid profiles of blood over time and biomarkers associated with non-alcoholic steatohepatitis in STAM mice

Characterization of behavioral phenotypes in the BTBR T+ Itpr3tf/J mouse model of autism spectrum disorder under social housing conditions using the multiple animal positioning system

Development of blastocyst complementation technology without contributions to gametes and the brain

mRNA and piRNA profile in chemical-induced oral squamous cell carcinoma mice model.

Deletion of the Tensin2 SH2-PTB domain, but not the loss of its PTPase activity, induces podocyte injury in FVB/N mouse strain

Genetic diversity of 21 experimental chicken lines with diverse origins and genetic backgrounds

Muscle weakness and impaired motor coordination in hyperpolarization-activated cyclic nucleotide-gated potassium channel 1-deficient rats

Neuron-specific Mafb knockout causes growth retardation accompanied by an impaired growth hormone/insulin-like growth factor I axis

Comparison of biological features between severely immuno-deficient NOD/Shi-scid Il2rgnull and NOD/LtSz-scid Il2rgnull mice

Generation of novel Il2rg-knockout mice with clustered regularly interspaced short palindromic repeats (CRISPR) and Cas9

Characterization of IL-17-producing T helper cells-like autoreactive T cells in aged mice

Establishment of a new formula for QT interval correction using a large colony of cynomolgus monkeys

Hairless-knockout piglets generated using the clustered regularly interspaced short palindromic repeat/CRISPR-associated-9 exhibit abnormalities in the skin and thymus

A rat model of serous borderline ovarian tumors induced by 7,12-dimethylbenz[a]anthracene

The comparison of two mouse models of inflammation-related lung tumorigenesis inducedby benzo(a)pyrene and lipopolysaccharide

Early attenuation of autonomic nervous function in senescence accelerated mouse-prone 8 (SAMP8)

Basic mouse reproductive techniques developed and modified at the Center for Animal Resources and Development (CARD), Kumamoto University

A simplified enriched environment increases body temperature and suppresses cancer progression in mice

Negative lusitropic property of nifekalant identified using ventricular pressure-volume loop analyses in anesthetized monkeys

A C1976Y missense mutation in the mouse Ip3r1 gene leads to short-term mydriasis and unfolded protein response in the iris constrictor muscles

Genetic modifiers of rodent animal models: the role in cataractogenesis

A new experimental mouse model of water intoxication with sustained increased intracranial pressure and mild hyponatremia without side effects of antidiuretics

Effects of environmental enrichment on autonomic nervous activity in NSY mice

Effects of triclosan on antioxidant- and apoptosis-related genes expression in the gill and ovary of zebrafish

Retraction: Preventive effects of risedronate and calcitriol on cancellous osteopenia in ratstreated with high-dose glucocorticoid

Development of a quantitative method for evaluating small intestinal motility using ultrasonography in mice

A semi-nested RT-PCR assay for detection of norovirus in rat fecal samples

Young Scientist Award

Fetal and early postnatal development of the porcine tonsils of the soft palate

Mouse NC/Jic strain provides novel insights into host genetic factors for malaria research

Poor mother-offspring relationships in rats with Cacna1a mutation

Development of an organ bath technique for isolated rat pancreas preparations to assess the effect of 1,5-AG on insulin secretion

Oral supplementation of L-glutathione prevents ultraviolet B-induced melanogenesis and oxidative stress in BALB/c mice

The effect of fish and mealworm larvae meals as alternative dietary protein sources on nutrient digestibility and gastrointestinal function in Chinchilla lanigera

Paromomycin sulfate is an effective treatment for balantidiasis in captive cynomolgus monkeys

Genetic mutation of Frem3 does not cause Fraser syndrome in mice

The effect of avertin anesthesia and a mixture of three types of anesthetic agents on food intakeand body weight in high fat-induced obese maleand female mice