Increased plasma neurofilament light chain concentration correlates with severity of post-mortem neurofibrillary tangle pathology and neurodegeneration
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-018-0649-3
Intersection of pathological tau and microglia at the synapse
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0754-y
Complement 3+-astrocytes are highly abundant in prion diseases, but their abolishment led to an accelerated disease course and early dysregulation of microglia
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0735-1
Low-level blast exposure disrupts gliovascular and neurovascular connections and induces a chronic vascular pathology in rat brain
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-018-0647-5
Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0742-2
The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention?
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0682-x
Phase I and phase II sonidegib and vismodegib clinical trials for the treatment of paediatric and adult MB patients: a systemic review and meta-analysis
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0773-8
Total copy number variation as a prognostic factor in adult astrocytoma subtypes
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0746-y
Detection of Alzheimer’s disease (AD) specific tau pathology with conformation-selective anti-tau monoclonal antibody in co-morbid frontotemporal lobar degeneration-tau (FTLD-tau)
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0687-5
In vivo real-time dynamics of ATP and ROS production in axonal mitochondria show decoupling in mouse models of peripheral neuropathies
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0740-4
Tenascin-C expression contributes to pediatric brainstem glioma tumor phenotype and represents a novel biomarker of disease
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0727-1
Unique α-synuclein pathology within the amygdala in Lewy body dementia: implications for disease initiation and progression
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0787-2
Understanding the pathogenesis of multiple system atrophy: state of the art and future perspectives
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0730-6
In vivo detection of tau fibrils and amyloid β aggregates with luminescent conjugated oligothiophenes and multiphoton microscopy
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0832-1
Organotypic slice culture model demonstrates inter-neuronal spreading of alpha-synuclein aggregates
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0865-5
Drosophila Ref1/ALYREF regulates transcription and toxicity associated with ALS/FTD disease etiologies
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0710-x
Phosphorylated TDP-43 aggregates in skeletal and cardiac muscle are a marker of myogenic degeneration in amyotrophic lateral sclerosis and various conditions
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0824-1
Hippocampal CA2 Lewy pathology is associated with cholinergic degeneration in Parkinson’s disease with cognitive decline
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0717-3
Glial pathology and retinal neurotoxicity in the anterior visual pathway in experimental autoimmune encephalomyelitis
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0767-6
c-MYC overexpression induces choroid plexus papillomas through a T-cell mediated inflammatory mechanism
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0739-x
The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer’s disease
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0660-3
Emergence of synaptic and cognitive impairment in a mature-onset APP mouse model of Alzheimer’s disease
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0670-1
BRAF V600E mutation in Juvenile Xanthogranuloma family neoplasms of the central nervous system (CNS-JXG): a revised diagnostic algorithm to include pediatric Erdheim-Chester disease
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0811-6
A soluble tau fragment generated by caspase-2 is associated with dementia in Lewy body disease
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0765-8
Assembly of transgenic human P301S Tau is necessary for neurodegeneration in murine spinal cord
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0695-5
Perfusion fixation in brain banking: a systematic review
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0799-y
A simplified approach using Taqman low-density array for medulloblastoma subgrouping
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0681-y
Blood brain barrier leakage is not a consistent feature of white matter lesions in CADASIL
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0844-x
H3F3A-G34R mutant high grade neuroepithelial neoplasms with glial and dysplastic ganglion cell components
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0731-5
Aldehyde dehydrogenase 2 activity and aldehydic load contribute to neuroinflammation and Alzheimer’s disease related pathology
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0839-7
Polarizing receptor activation dissociates fibroblast growth factor 2 mediated inhibition of myelination from its neuroprotective potential
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0864-6
Aβ43 in human Alzheimer’s disease: effects of active Aβ42 immunization
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0791-6
Dynein activating adaptor BICD2 controls radial migration of upper-layer cortical neurons in vivo
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0827-y
Neurodegeneration and contralateral α-synuclein induction after intracerebral α-synuclein injections in the anterior olfactory nucleus of a Parkinson’s disease A53T mouse model
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0713-7
Absence of endothelial α5β1 integrin triggers early onset of experimental autoimmune encephalomyelitis due to reduced vascular remodeling and compromised vascular integrity
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0659-9
Deep morphological analysis of muscle biopsies from type III glycogenesis (GSDIII), debranching enzyme deficiency, revealed stereotyped vacuolar myopathy and autophagy impairment
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0815-2
Synergistic toxicity in an in vivo model of neurodegeneration through the co-expression of human TDP-43M337V and tauT175D protein
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0816-1
Mice deficient in the C-terminal domain of TAR DNA-binding protein 43 develop age-dependent motor dysfunction associated with impaired Notch1−Akt signaling pathway
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0776-5
C-terminal and full length TDP-43 specie differ according to FTLD-TDP lesion type but not genetic mutation
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0755-x
Microglia pre-activation and neurodegeneration precipitate neuroinflammation without exacerbating tissue injury in experimental autoimmune encephalomyelitis
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0667-9
Region-specific interneuron demyelination and heightened anxiety-like behavior induced by adolescent binge alcohol treatment
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0829-9
Sleep deprivation of rats increases postsurgical expression and activity of L-type calcium channel in the dorsal root ganglion and slows recovery from postsurgical pain
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0868-2
Optimization of ultrastructural preservation of human brain for transmission electron microscopy after long post-mortem intervals
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0794-3
Clinicopathological features of the rare form of Creutzfeldt-Jakob disease in R208H-V129V PRNP carrier
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0699-1
HR23B pathology preferentially co-localizes with p62, pTDP-43 and poly-GA in C9ORF72-linked frontotemporal dementia and amyotrophic lateral sclerosis
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0694-6
N368-Tau fragments generated by legumain are detected only in trace amount in the insoluble Tau aggregates isolated from AD brain
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0831-2
An AARS variant as the likely cause of Swedish type hereditary diffuse leukoencephalopathy with spheroids
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0843-y
Mapping actionable pathways and mutations in brain tumours using targeted RNA next generation sequencing
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0826-z
Correction to: Retinal pathology in experimental optic neuritis is characterized by retrograde degeneration and gliosis
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0825-0
Enhanced phosphorylation of T153 in soluble tau is a defining biochemical feature of the A152T tau risk variant
来源期刊:Acta Neuropathologica CommunicationsDOI:10.1186/s40478-019-0661-2